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News About Protocatechuic_acid

09-SEPTEMBER-2008 19:33:10 - Protocatechuic acid Protocatechuic acid IUPAC name 3,4-Dihydroxybenzoic acid Identifiers CAS number 99-50-3 PubChem 72 SMILES C1=CC=CC=C1C=OOOO Properties Molecular formula C7H6O4 Molar mass 154.12014 Except where noted otherwise, data are given for materials in their standard state at 25 °C, 100 kPa Infobox references Protocatechuic acid PCA is an polyphenol antioxidant found in roselle. Data on the biological activity of PCA are contradictory with both anti-tumor and tumor-promoting effects observed in in vitro studies. For example, PCA has been shown to induce apoptosis of human leukemia cells, as well as malignant HSG1 cells taken from human oral cavities.1 However, PCA enhances tumor promotion in mouse skin cells.2 References ^ Babich H, Sedletcaia A, Kenigsberg B November 2002. In vitro cytotoxicity of protocatechuic acid to cultured human cells from oral tissue: involvement in oxidative stress. Pharmacol. Toxicol. 91 5: 245-53. PMID 12570031. ^ Nakamura Y, Torikai K, Ohto Y, Murakami A, Tanaka T, Ohigashi H October 2000. A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase. Carcinogenesis 21 10: 1899-907. PMID 11023549. Retrieved from http://en..org/wiki/Protocatechuic_acid Categories: Antioxidants | Benzoic acids | Benzenediols Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Français This page was last modified on 7 August 2008, at 21:04

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