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14-September-2008 18:02:43 - G protein-coupled receptor 3 Identifiers Symbols GPR3; ACCA External IDs OMIM: 600241 MGI: 101908 HomoloGene: 31303 Gene ontology Molecular function: rhodopsin-like receptor activity receptor activity Cellular component: integral to plasma membrane membrane Biological process: signal transduction G-protein coupled receptor protein signaling pathway G-protein signaling, adenylate cyclase activating pathway RNA expression pattern More reference expression data Orthologs Human Mouse Entrez 2827 14748 Ensembl ENSG00000181773 ENSMUSG00000049649 Uniprot P46089 Q3USD4 Refseq NM_005281 mRNA NP_005272 protein NM_008154 mRNA NP_032180 protein Location Chr 1: 27.59 - 27.59 Mb Chr 4: 132.48 - 132.48 Mb Pubmed search 1 2 G protein-coupled receptor 3, also known as GPR3, is a human gene.1 References ^ Entrez Gene: GPR3 G protein-coupled receptor 3. Further reading Eggerickx D, Denef JF, Labbe O, et al. 1995. Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.. Biochem. J. 309 Pt 3: 837-43. PMID 7639700. Iismaa TP, Kiefer J, Liu ML, et al. 1995. Isolation and chromosomal localization of a novel human G-protein-coupled receptor GPR3 expressed predominantly in the central nervous system.. Genomics 24 2: 391-4. doi:10.1006/geno.1994.1635. PMID 7698767. Heiber M, Docherty JM, Shah G, et al. 1995. Isolation of three novel human genes encoding G protein-coupled receptors.. DNA Cell Biol. 14 1: 25-35. PMID 7832990. Marchese A, Docherty JM, Nguyen T, et al. 1995. Cloning of human genes encoding novel G protein-coupled receptors.. Genomics 23 3: 609-18. doi:10.1006/geno.1994.1549. PMID 7851889. Song ZH, Modi W, Bonner TI 1996. Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors.. Genomics 28 2: 347-9. doi:10.1006/geno.1995.1154. PMID 8530049. Strausberg RL, Feingold EA, Grouse LH, et al. 2003. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 99 26: 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. Uhlenbrock K, Huber J, Ardati A, et al. 2003. Fluid shear stress differentially regulates gpr3, gpr6, and gpr12 expression in human umbilical vein endothelial cells.. Cell. Physiol. Biochem. 13 2: 75-84. doi:10.1159/000070251. PMID 12649592. Gerhard DS, Wagner L, Feingold EA, et al. 2004. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection MGC.. Genome Res. 14 10B: 2121-7. doi:10.1101/gr.2596504. PMID 15489334. Gregory SG, Barlow KF, McLay KE, et al. 2006. The DNA sequence and biological annotation of human chromosome 1.. Nature 441 7091: 315-21. doi:10.1038/nature04727. PMID 16710414. This transmembrane receptor-related article is a stub. v d e Transmembrane receptor: G protein-coupled receptors Class A: Rhodopsin like Adrenergic α1 A, B, D, α2 A, B, C, β1, β2, β3 Eicosanoid CysLT 1, 2, LTB4 1, 2, FPRL1, OXE, Prostaglandin DP, EP 1, 2, 3, 4, PGF, Prostacyclin, Thromboxane Neuropeptide B/W 1, 2, FF 1, 2, S, Y 1, 2, 4, 5 Orphan GPR 1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 79, 82, 83, 84, 85, 87, 88, 92, 101, 103, 119, 120, 132, 135, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 172, 173, 174, 176, 177, 182 Purinergics Adenosine A1, A2a, A2b, A3, P2Y, 1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14 Serotonin all but 5-HT3 5-HT1 A, B, D, E, F, 5-HT2 A, B, C, 5-HT 4, 5A, 6, 7 Other Acetylcholine M1, M2, M3, M4, M5 - Adrenomedullin - Anaphylatoxin C3a, C5a - Angiotensin 1, 2 - Apelin - Bile acid - Bombesin BRS3, GRPR, NMBR - Bradykinin B1, B2 - Cannabinoid CB1, CB2 - Chemokine - Cholecystokinin A, B - Dopamine D1, D2, D3, D4, D5 - EBI2 - Endothelin A, B - Estrogen - Formyl peptide 1, L1, L2 - Free fatty acid 1, 2, 3, 4 - FSH - Galanin 1, 2, 3 - Gonadotropin-releasing hormone 1, 2 - Ghrelin - Histamine H1, H2, H3, H4 - Kisspeptin - Luteinizing hormone/choriogonadotropin - Lysophospholipid 1, 2, 3, 4, 5, 6, 7, 8 - MAS 1, 1L, D, E, F, G, X1, X2, X3, X4 - Melanocortin 1, 2, 3, 4, 5 - MCHR 1, 2 - Melatonin 1A, 1B- Motilin - neuromedin B, U 1, 2 - Neurotensin 1, 2 - Opioid Delta, Kappa, Mu, Nociceptin, but not Sigma - Olfactory - Opsin 3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH - Orexin 1, 2 - Oxytocin - Oxoglutarate - PAF - Prokineticin 1, 2 - Prolactin-releasing peptide - Protease-activated 1, 2, 3, 4 - Relaxin 1, 2, 3, 4 - Somatostatin 1, 2, 3, 4, 5 - SREB - Succinate - TAAR 1, 2, 3, 5, 6, 8, 9 - Tachykinin 1, 2, 3 - Thyrotropin - Thyrotropin-releasing hormone - Urotensin-II - Vasopressin 1A, 1B, 2 Class B: Secretin like Brain-specific angiogenesis inhibitor 1, 2, 3 - Cadherin 1, 2, 3 - Calcitonin - CD97 - Corticotropin-releasing hormone 1, 2 - EMR 1, 2, 3 - Glucagon GR, GIPR, GLP1R, GLP2R - Growth hormone releasing hormone - PACAPR1- GPR 56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 157 - Latrophilin 1, 2, 3, ELTD1 - Parathyroid hormone 1, 2 - Secretin - Vasoactive intestinal peptide 1, 2 Class C: Metabotropic glutamate / pheromone Calcium-sensing receptor - GABA B 1, 2 - Glutamate receptor Metabotropic glutamate 1, 2, 3, 4, 5, 6, 7, 8 - GPRC6A - GPR 156, 158, 179 - RAIG 1, 2, 3, 4 - Taste receptors TAS1R 1, 2, 3 TAS2R 1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 38, 39, 40, 41, 43, 44, 45, 46, 47, 48, 49, 50 Frizzled / Smoothened Frizzled 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 - Smoothened Retrieved from http://en..org/wiki/GPR3 Categories: Genes on chromosome 1 | Human proteins | Transmembrane receptor stubs | G protein coupled receptorsHidden category: Protein pages needing a picture Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 8 July 2008, at 13:16
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