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News About Lipotropin

14-September-2008 18:02:47 - Lipotropin proopiomelanocortin adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin Identifiers Symbol POMC Entrez 5443 HUGO 9201 OMIM 176830 RefSeq NM_000939 UniProt P01189 Other data Locus Chr. 2 p23 Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin POMC. The anterior pituitary gland produces the pro-hormone POMC, which undergoes cleavage to adrenocorticotropin ACTH and β-lipotropin β-LPH. Contents 1 Beta-lipotropin 2 Gamma-lipotropin 3 External links 4 References Beta-lipotropin β-lipotropin is a 90 amino acid polypeptide that is the carboxy-terminal fragment of POMC. It stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides. In humans, γ-lipotropin, α-MSH, β-MSH, γ-MSH, α-endorphin, β-endorphin, γ-endorphin, and met-enkephalin are all possible fragments of β-lipotropin.1 β-lipotropin also performs lipid-mobilizing functions such as lipolysis and steroidogenesis. Gamma-lipotropin γ-lipotropin is the amino-terminal peptide fragment of β-lipotropin. In humans, it has 56 amino acids. External links MeSH beta-Lipotropin MeSH gamma-Lipotropin References ^ Joachim Spiess, Charles D. Mount, Wendell E. Nicholson, David N. Orth 1982, NH2-Terminal amino acid sequence and peptide mapping of purified human β-lipotropin: Comparison with previously proposed sequences, Proc. Natl. Acad. Sci. USA 79: 5071-5, http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=346829blobtype=pdf. Retrieved on 21 June 2007 This biology article is a stub. v d e Endocrine system: hormones/endocrine glands Peptide hormones, Steroid hormones Hypothalamic-pituitary Hypothalamus: TRH, CRH , GnRH, GHRH, somatostatin, dopamine - Posterior pituitary: vasopressin, oxytocin - Anterior pituitary: α FSH, LH, TSH, GH, prolactin, POMC ACTH, MSH, endorphins, lipotropin Adrenal axis Adrenal medulla: epinephrine, norepinephrine - Adrenal cortex: aldosterone, cortisol, DHEA Thyroid axis Thyroid: thyroid hormone T3 and T4 - calcitonin - Parathyroid: PTH Gonadal axis Testis: testosterone, AMH, inhibin - Ovary: estradiol, progesterone, inhibin/activin, relaxin pregnancy Other end. glands Pancreas: glucagon, insulin, somatostatin - Pineal gland: melatonin Non-end. glands Placenta: hCG, HPL, estrogen, progesterone - Kidney: renin, EPO, calcitriol, prostaglandin - Heart atrium: ANP - Stomach: gastrin, ghrelin - Duodenum: CCK, GIP, secretin, motilin, VIP - Ileum: enteroglucagon - Adipose tissue: leptin, adiponectin, resistin - Thymus: Thymosin - Thymopoietin - Thymulin - Skeleton: Osteocalcin - Liver/other: Insulin-like growth factor IGF-1, IGF-2 Target-derived NGF, BDNF, NT-3 v d e Peptides: neuropeptides Hypothalamic Somatostatin - CRH - GnRH - GHRH - Orexins - TRH - POMC ACTH, MSH, Lipotropin Gastrointestinal hormones Cholecystokinin - Gastric inhibitory polypeptide - Gastrin - Motilin - Secretin - Vasoactive intestinal peptide Other hormones Vasopressin - Calcitonin - Other Angiotensin - Bombesin/Neuromedin B - Calcitonin gene-related peptide - Carnosine - Delta sleep-inducing peptide - FMRFamide - Galanin - Gastrin releasing peptide - Kinins Bradykinin, Tachykinins - Neuromedin B, N, U - Neuropeptide Y - Neurophysins - Neurotensin - Opioid peptide - Pancreatic polypeptide - Pituitary adenylate cyclase activating peptide Retrieved from http://en..org/wiki/Lipotropin Categories: Genes on chromosome 2 | Biology stubsHidden category: Protein pages needing a picture Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Þ‹Þ¨ÞˆÞ¬Þ€Þ¨Þ„Þ¦Þ?Þ° This page was last modified on 5 February 2008, at 15:43

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