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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
14-September-2008 18:02:48 - PAH clearance Para aminohippurate clearance or PAH clearance is a method used in renal physiology to measure renal plasma flow, which, in turn, is a measure of renal function. The concentration of para aminohippurate PAH is measured in one arterial blood sample PPAH and one urine sampleUPAH. The urine flow V as also measured. Renal perfusion flow is then calculated by: RPF = \fracU_PAHP_PAH V What in fact is calculated is the effective renal plasma flow eRPF. However, since the renal extraction ratio of PAH almost equals 1, then eRPF almost equals RPF. Precision The renal extraction ratio of PAH in a normal individual is approximately 0.921, and thus not exactly 1.0. Thus, this method usually underestimates RPF by approximately 10%. This margin of error is generally acceptable considering the ease with which eRPF is measured. References ^ Reubi FC. Glomberular Filtration Rate, Renal Blood Flow and Blood Viscosity during and after Diabetic Coma. Circ. Res. 1953;1;410-413. Available at: http://circres.ahajournals.org/cgi/reprint/1/5/410.pdf. Accessed on: May 2, 2007. v d e Urinary system, physiology: renal physiology and acid base physiology Filtration Renal blood flow - Ultrafiltration - Countercurrent exchange Hormones affecting filtration Antidiuretic hormone ADH - Aldosterone - Atrial natriuretic peptide Secretion/clearance Pharmacokinetics - Clearance of medications Reabsorption Solvent drag - Na+ - Cl- - urea - glucose - oligopeptides - protein Endocrine Renin - Erythropoietin EPO - Calcitriol Active vitamin D - Prostaglandins Assessing Renal function/ Measures of dialysis Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance Effective renal plasma flow - Extraction ratio Acid base physiology Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas Buffering/compensation Bicarbonate buffering system - Respiratory compensation - Renal compensation Retrieved from http://en..org/wiki/PAH_clearance Categories: Renal physiology | Medical tests Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 15 June 2008, at 07:22
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