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14-September-2008 18:02:40 - Radiopharmacology Redirected from Radiopharmaceuticals Radiopharmacology is the study and preparation of radiopharmaceuticals, which are radioactive pharmaceuticals. Radiopharmaceuticals are used in the field of nuclear medicine as tracers in the diagnosis and treatment of many diseases. Many radiopharmaceuticals use technetium Tc-99m. In the book Technetium by Klaus Schwochau, 31 different radiopharmaceuticals based on Tc-99m are listed for imaging and functional studies of the brain, myocardium, thyroid, lungs, liver, gallbladder, kidneys, skeleton, blood and tumors. A list of nuclear medicine radiopharmaceuticals follows. Some radioisotopes are used in ionic or inert form without attachment to a pharmaceutical, these are also included. There is a section for each radioisotope with a table of radiopharmaceuticals using that radioisotope. The sections are ordered alphabetically by the English name of the radioisotope. Sections for the same element are then ordered by atomic mass number. Not all radionuclides, the radioactive portion of a radiopharmaceutical, are technically isotopes. Although, they are commonly referred to as such. SEE Isotope Contents 1 Calcium-47 2 Carbon-11 3 Carbon-14 4 Chromium-51 5 Cobalt-57 6 Cobalt-58 7 Erbium-169 8 Fluorine-18 9 Gallium-67 10 Hydrogen-3 11 Indium-111 12 Iodine-123 13 Iodine-131 13.1 Diagnostic 13.2 Therapeutic 14 Iron-59 15 Krypton-81m 16 Nitrogen-13 17 Oxygen-15 18 Phosphorus-32 19 Samarium-153 20 Selenium-75 21 Sodium-22 22 Sodium-24 23 Strontium-89 24 Technetium-99m 25 Thallium-201 26 Xenon-133 27 Yttrium-90 28 References Calcium-47 47Ca is a beta and gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Ca-47-Ca2+ Bone metabolism IV In-vitro Not all radionuclides, the radioactive portion of a radiopharmaceutical, are technically isotopes. Although, they are commonly referred to as such. SEE Isotope Non-imaging Carbon-11 11C is a positron emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging C11-L-methyl-methionine Brain tumour imaging Parathyroid imaging IV In-vivo Imaging Carbon-14 14C is a beta emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging C14-Glycocholic acid Breath test for small intestine bacterial overgrowth Oral In-vitro Non-imaging C14-PABA para-amino benzoic acid Pancreatic studies Oral In-vitro Non-imaging C14-Urea Breath test to detect Helicobacter pylori Oral In-vitro Non-imaging C14-d-xylose Breath test for small intestine bacterial overgrowth Oral In-vitro Non-imaging Chromium-51 51Cr is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Cr51-Red blood cells Red cell volume; sites of sequestration; gastrointestinal blood loss IV In-vitro Non-imaging Cr51-Cr3+ Gastrointestinal protein loss IV In-vitro Non-imaging Cr51-EDTA ethylenediaminetetraacetic acid Glomerular filtration rate measurement IV In-vitro Non-imaging Cobalt-57 57Co is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Co57-Cyanocobalamin vitamin B12 Gastrointestinal absorption Oral In-vitro Non-imaging Cobalt-58 58Co is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Co58-Cyanocobalamin vitamin B12 Gastrointestinal absorption Oral In-vitro Non-imaging Erbium-169 169Er is a beta emitter. Name Treatment of Route of administration Er169-Colloid Arthritic conditions Intra-articular Fluorine-18 18F is a positron emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging F18-FDG Fluorodeoxyglucose Tumour imaging Myocardial imaging IV In-vivo Imaging F18-Fluoride Bone imaging IV In-vivo Imaging Gallium-67 67Ga is a gamma emitter. See Gallium scan. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Ga67-Ga3+ Tumour imaging IV In-vivo Imaging Ga67-Ga3+ Infection/inflammation imaging IV In-vivo Imaging Hydrogen-3 3H or tritium is a beta emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging H3-water Total body water Oral or IV In-vitro Non-imaging Indium-111 111In is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging In111-DTPA diethylenetriaminepenta-acetic acid GI transit Oral In-vivo Imaging In111-DTPA diethylenetriaminepenta-acetic acid Cisternography Intra-cisternal In-vivo Imaging In111-Leucocytes Infection/inflammation imaging IV In-vivo Imaging In111-Platelets Thrombus imaging IV In-vivo Imaging In111-Pentetreotide Somatostatin receptor imaging IV In-vivo Imaging Iodine-123 123I is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging I123-Iodide Thyroid uptake Oral or IV In-vivo Non-imaging I123-Iodide Thyroid imaging Thyroid metastases imaging Oral or IV In-vivo Imaging I123-o-Iodohippurate Renal imaging IV In-vivo Imaging I123-MIBG m-iodobenzylguanidine Neuroectodermal tumour imaging IV In-vivo Imaging I123-FP-CIT SPECT imaging of Parkinson's Disease IV In-vivo Imaging Iodine-131 131I is a beta and gamma emitter. Diagnostic Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging I131-Iodide Thyroid uptake Oral In-vivo Non-imaging I131-Iodide Thyroid metastases imaging Oral or IV In-vivo Imaging I131-MIBG m-iodobenzylguanidine Neuroectodermal tumour imaging IV In-vivo Imaging Therapeutic Name Treatment of Route of administration I131-Iodide Thyrotoxicosis IV or Oral I131-Iodide Non-toxic goitre IV or Oral I131-Iodide Thyroid carcinoma IV or Oral I131-MIBG m-iodobenzylguanidine Malignant disease IV Iron-59 59Fe is a beta and gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Fe59-Fe2+ or Fe3+ Iron metabolism IV In-vitro Non-imaging Krypton-81m 81Krm is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Kr81m-Gas Lung ventilation imaging Inhalation In-vivo Imaging Kr-81m-Aqueous solution Lung perfusion imaging IV In-vivo Imaging Nitrogen-13 13N is a positron emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging N13-Ammonia Myocardial blood flow imaging IV In-vivo Imaging Oxygen-15 15O is a positron emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging O15-Water Cerebral blood flow imaging Myocardial blood flow imaging IV bolus In-vivo Imaging Phosphorus-32 32P is a beta emitter. Name Treatment of Route of administration P32-Phosphate Polycythemia and related disorders IV or Oral Samarium-153 153Sm is a beta and gamma emitter. Name Treatment of Route of administration Sm153-EDTMP Ethylenediaminotetramethylenephosphoric acid Bone metastases IV Selenium-75 75Se is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Se75-Selenorcholesterol Adrenal gland imaging IV In-vivo Imaging Se75-SeHCAT 23-Seleno-25-homo-tauro-cholate Bile salt absorption Oral In-vivo Imaging Sodium-22 22Na is a positron and gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Na22-Na+ Electrolyte studies Oral or IV In-vitro Non-imaging Sodium-24 24Na is a beta and gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Na24-Na+ Electrolyte studies Oral or IV In-vitro Non-imaging Strontium-89 89Sr is a beta emitter. Name Treatment of Route of administration Sr89-Chloride Bone metastases IV Technetium-99m 99mTc is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Tc99m-pertechnetate Thyroid uptake and thyroid imaging Stomach and salivary gland imaging Meckel's diverticulum imaging Brain imaging Micturating cystogram First pass blood flow imaging First pass peripheral vascular imaging IV In-vivo Imaging Tc99m-pertechnetate Lacrimal imaging Eye drops In-vivo Imaging Tc99m-Human albumin Cardiac blood pool imaging IV In-vivo Imaging Tc99m-Human albumin Peripheral vascular imaging IV In-vivo Imaging Tc99m-Human albumin macroaggregates or microspheres Lung perfusion imaging IV In-vivo Imaging Tc99m-Human albumin macroaggregates or microspheres Lung perfusion imaging with venography IV In-vivo Imaging Tc99m-Phosphonates and phosphates Bone imaging IV In-vivo Imaging Tc99m-Phosphonates and phosphates Myocardial imaging IV In-vivo Imaging Tc99m-DTPA diethylenetriaminepenta-acetic acid Renal imaging First pass blood flow studies Brain imaging IV In-vivo Imaging Tc99m-DTPA diethylenetriaminepenta-acetic acid Lung ventilation imaging Aerosol inhalation In-vivo Imaging Tc99m-DMSAV dimercaptosuccinic acid Tumour imaging IV In-vivo Imaging Tc99m-DMSAIII dimercaptosuccinic acid Renal imaging IV In-vivo Imaging Tc99m-Colloid Bone marrow imaging GI Bleeding IV In-vivo Imaging Tc99m-Colloid Lymph node imaging Interstitial In-vivo Imaging Tc99m-Colloid Oesophageal transit and reflux imaging Oral In-vivo Imaging Tc99m-Colloid Lacrimal imaging Eye drops In-vivo Imaging Tc99m-HIDA Hepatic iminodiacetic acid Functional biliary system imaging IV In-vivo Imaging Tc99m-Denatured red bood cells Red cell volume IV In-vitro Non-imaging Tc99m-Red blood cells GI bleeding Cardiac blood pool imaging Peripheral vascular imaging IV In-vivo Imaging Tc99m-MAG3 mercaptoacetyltriglycine Renal imaging First pass blood flow imaging IV In-vivo Imaging Tc99m-HMPAO Hexamethyl-propylene amine oxime Cerebral blood flow imaging IV In-vivo Imaging Tc99m-HMPAO Hexamethyl-propylene amine oxime labelled leucocytes Infection/inflammation imaging IV In-vivo Imaging Tc99m-Sestamibi Parathyroid imaging Non-specific tumour imaging Thyroid tumour imaging Breast imaging Myocardial imaging IV In-vivo Imaging Tc99m-Sulesomab IMMU-MN3 murine Fab'-SH antigranulocyte monoclonal antibody fragments Infection/inflammation imaging IV In-vivo Imaging Tc99m-Technegas Lung ventilation imaging Inhalation In-vivo Imaging Tc99m-Human immunoglobulin Infection/inflammation imaging IV In-vivo Imaging Tc99m-Tetrofosmin Parathyroid imaging Myocardial imaging IV In-vivo Imaging Tc99m-ECD ethyl cysteinate dimer Brain imaging IV In-vivo Imaging Thallium-201 201Tl is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Tl201-Tl+ Non-specific tumour imaging Thyroid tumour imaging Myocardial imaging Parathyroid imaging IV In-vivo Imaging Xenon-133 133Xe is a gamma emitter. Name Investigation Route of administration In-vitro / in-vivo Imaging / non-imaging Xe133-gas Lung ventilation studies Inhalation In-vivo Imaging Xe133 in isotonic sodium chloride solution Cerebral blood flow IV In-vivo Imaging Yttrium-90 90Y is a beta emitter. Name Treatment of Route of administration Y90-Silicate Arthritic conditions Intra-articular Y90-Silicate Malignant disease Intracavitary References Notes for guidance on the clinical administration of radiopharmaceuticals and use of sealed radioactive sources. Administration of radioactive substances advisory committee. December 1998. Produced by the National Radiological Protection Board. Malabsorption. In: The Merck Manual of Geriatrics, chapter 111. Leukoscan summary of product characteristics Tc99m-Sulesomab. Schwochau, Klaus. Technetium. Wiley-VCH 2000. ISBN 3-527-29496-1 Retrieved from http://en..org/wiki/Radiopharmacology Categories: Nuclear medicine | Radiobiology | Radiation oncology Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch This page was last modified on 2 September 2008, at 16:5
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