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14-September-2008 18:02:40 - Remikiren Remikiren Systematic IUPAC name 2R-2-tert-butylsulfonylmethyl-N-2S-1- 2R,3S,4R-1-cyclohexyl-4-cyclopropyl-3,4- dihydroxybutan-2-ylamino-3-3H-imidazol- 4-yl-1-oxopropan-2-yl-3-phenylpropanamide Identifiers CAS number 126222-34-2 ATC code C09XA01 PubChem 5462340 DrugBank APRD00163 Chemical data Formula C33H50N4O6S Mol. mass 630.839 g/mol Pharmacokinetic data Bioavailability ? Protein binding 83% Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Remikiren is a renin inhibitor under development for the treatment of hypertension high blood pressure. It was first developed by Hoffmann-La Roche in 1996.1 References ^ Richter WF, Whitby BR, Chou RC 1996. Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals. Xenobiotica 26 3: 243-54. PMID 8730917. Structure of captopril, the first clinically successful ACE inhibitor This antihypertensive-related article is a stub. v d e Agents acting on the renin-angiotensin system C09 ACE inhibitors Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Fosinopril Imidapril Lisinopril Moexipril Perindopril Quinapril Ramipril Rentiapril Spirapril Temocapril Trandolapril Zofenopril Angiotensin II receptor antagonists AIIRA Azilsartan Candesartan Eprosartan Irbesartan Losartan Olmesartan Tasosartan Telmisartan Valsartan Renin inhibitors Aliskiren Remikiren Retrieved from http://en..org/wiki/Remikiren Categories: Antihypertensive agent stubs | Renin inhibitors Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Magyar This page was last modified on 25 May 2008, at 13:49
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