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News About Renal_urea_handling

14-September-2008 18:02:48 - urea handling Renal urea handling is the part of renal physiology that deals with the reabsorption and secretion of urea. Urea allows the body to create hyperosmotic urine urine that has more ions in it--is more concentrated--than that same person's blood plasma. Preventing the loss of water in this manner is important if the person's body needs to save water in order to maintain a suitable blood pressure or more likely, in order to maintain a suitable concentration of sodium ions in the blood plasma. About half of the urea filtered 40%1 is normally found in the final urine, since there is more reabsorption than secretion along the nephron. It is regulated by antidiuretic hormone, which controls the amount reabsorbed in the collecting duct system and secreted into the loop of Henle. Overview table Characteristic proximal tubule loop of Henle Distal convoluted tubule Collecting duct system S1 S2 S3 descending limb thin ascending limb thick ascending limb connecting tubule initial collecting tubule cortical collecting ducts medullary collecting ducts reabsorption % compared to filtered amount 501 70 secretion % compared to filtered amount 601 reabsorption mmoles/day Concentration electrical driving force mV -32 +32 +152 -5 to +52 -402 chemical driving force mV electrochemical driving force mV apical transport proteins solvent drag1 unknown transporter1 Urea transporter 2?1 unknown transporter1 urea transporter 11 basolateral transport proteins unknown transporter1 Urea transporter 2?1 unknown transporter1 urea transporter 41 Other reabsorption features References ^ a b c d e f g h i j k l Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 791 ^ a b c d e Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 777 v d e Urinary system, physiology: renal physiology and acid base physiology Filtration Renal blood flow - Ultrafiltration - Countercurrent exchange Hormones affecting filtration Antidiuretic hormone ADH - Aldosterone - Atrial natriuretic peptide Secretion/clearance Pharmacokinetics - Clearance of medications Reabsorption Solvent drag - Na+ - Cl- - urea - glucose - oligopeptides - protein Endocrine Renin - Erythropoietin EPO - Calcitriol Active vitamin D - Prostaglandins Assessing Renal function/ Measures of dialysis Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance Effective renal plasma flow - Extraction ratio Acid base physiology Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas Buffering/compensation Bicarbonate buffering system - Respiratory compensation - Renal compensation Retrieved from http://en..org/wiki/Renal_urea_handling Categories: Physiology Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 25 February 2008, at 18:58

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