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News About Ebselen

22-AUGUST-2008 06:13:22 - Ebselen Ebselen Skeletal formula of ebselen Ball-and-stick model of the ebselen molecule IUPAC name 2-Phenyl-1,2-benzoselenazol-3-one Identifiers CAS number 60940-34-3 PubChem 3194 SMILES C1=CC=CC=C1N2C=OC3=CC=CC=C3Se2 Properties Molecular formula C13H9NOSe Molar mass 274.17666 Except where noted otherwise, data are given for materials in their standard state at 25 °C, 100 kPa Infobox references Ebselen or 2-phenyl-1, 2-benzisoselenazol-32H-one also called PZ 51 or DR3305, is a mimic of glutathione peroxidase and can also react with peroxynitrite.1 It is being investigated as a possible treatment for reperfusion injury and stroke.23 References ^ Schewe T 1995. Molecular actions of ebselen--an antiinflammatory antioxidant. Gen Pharmacol 26 6: 1153-69. PMID 7590103. ^ Parnham M, Sies H 2000. Ebselen: prospective therapy for cerebral ischaemia. Expert Opin Investig Drugs 9 3: 607-19. doi:10.1517/13543784.9.3.607. PMID 11060699. ^ Yamaguchi T, Sano K, Takakura K, Saito I, Shinohara Y, Asano T, Yasuhara H 1998. Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke 29 1: 12-7. PMID 9445321. This biochemistry article is a stub. Retrieved from http://en..org/wiki/Ebselen Categories: Selenium compounds | Biochemistry stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 7 June 2008, at 16:08. of the GNU Free Documentation License. ® , Inc., a U.S.

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