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20-September-2008 09:55:58 - C-acyltransferase acetyl-Coenzyme A acyltransferase 1 peroxisomal 3-oxoacyl-Coenzyme A thiolase Identifiers Symbol ACAA1 Entrez 30 HUGO 82 OMIM 604054 RefSeq NM_001607 UniProt P09110 Other data EC number 2.3.1.16 Locus Chr. 3 p23-p22 acetyl-Coenzyme A acyltransferase 2 mitochondrial 3-oxoacyl-Coenzyme A thiolase Identifiers Symbol ACAA2 Entrez 10449 HUGO 83 OMIM 604770 RefSeq NM_006111 UniProt P42765 Other data EC number 2.3.1.16 Locus Chr. 18 1 The final step of beta oxidation is the cleavage of 3-ketoacyl CoA by the thiol group of another molecule of CoA. This reaction is catalyzed by Acetyl-CoA C-acyltransferase or Β-ketothiolase. The thiol is inserted between C-2 and C-3, which yields an acetyl CoA molecule and an acyl CoA molecule, which is two carbons shorter. Mevalonate pathway Mevalonate pathway Ketogenesis Ketogenesis External links MeSH Acetyl-CoA+C-Acyltransferase This transferase article is a stub. v d e Transferases: acyltransferases EC 2.3 2.3.1: other than amino-acyl groups mostly acetyltransferases N-Acetylglutamate synthase - Choline acetyltransferase - Acetyl-Coenzyme A acetyltransferase - Dihydrolipoyl transacetylase - Acetyl-CoA C-acyltransferase - Beta-galactoside transacetylase - Carnitine O-palmitoyltransferase CPT1, CPT2 - Acyltransferase like 2 - Chloramphenicol acetyltransferase - Aminolevulinic acid synthase - Beta-ketoacyl-ACP synthase - Glyceronephosphate O-acyltransferase - Lecithin-cholesterol acyltransferase - Histone acetyltransferase P300/CBP - Serotonin N-acetyl transferase - Serine C-palmitoyltransferase SPTLC1, SPTLC2 - HGSNAT 2.3.2 - Aminoacyltransferases Gamma-glutamyl transpeptidase - Peptidyl transferase - Transglutaminase Tissue transglutaminase, Keratinocyte transglutaminase, Factor XIII 2.3.3 - converted into alkyl on transfer Citrate synthase - ATP citrate lyase - HMG-CoA synthase v d e Metabolism: lipid metabolism - triglyceride and fatty acid enzymes Lipid production ATP citrate lyase - Acetyl-CoA carboxylase Fatty acid synthesis/Fatty acid synthase: Beta-ketoacyl-ACP synthase - Β-Ketoacyl ACP reductase - 3-Hydroxyacyl ACP dehydrase - Enoyl ACP reductase triacyl glycerol: Glycerol-3-phosphate dehydrogenase - Thiokinase Lipid degradation Acyl transport: Carnitine palmitoyltransferase I - Carnitine-acylcarnitine translocase - Carnitine palmitoyltransferase II Beta oxidation/Mitochondrial trifunctional protein: Acyl CoA dehydrogenase ACADL, ACADM, ACADS, ACADVL - Enoyl-CoA hydratase - 3-Hydroxyacyl CoA dehydrogenase - Acetyl-CoA C-acyltransferase to acetyl-CoA: Malonyl-CoA decarboxylase unsaturated Enoyl CoA isomerase, 2,4 Dienoyl-CoA reductase odd chain Propionyl-CoA carboxylase aldehydes Long-chain-aldehyde dehydrogenase see also disorders Retrieved from http://en..org/wiki/Acetyl-CoA_C-acyltransferase Categories: Genes on chromosome 3 | Genes on chromosome 18 | Transferase stubsHidden category: Protein pages needing a picture Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 22 November 2007, at 00:55
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