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News About Alpha_4_beta_2_nicotinic_receptor

20-September-2008 09:55:55 - 4 beta-2 nicotinic receptor The alpha-4 beta-2 nicotinic receptor α42β23 is a type of nicotinic acetylcholine receptor, consisting of α4 and β2 subunits1. It is located in the brain, where activation yields post- and presynaptic excitation1, mainly by increased Na+ and K+ permeability. Agonists Nicotinic agonists for this receptor include: nicotine epibatidine acetylcholine cytosine ABT-089 ABT-418 dianicline ispronicline rivanicline tebanicline varenicline Antagonists mecamylamine methylaconitine α-conotoxin References ^ a b Pharmacology, Rang, Dale, Ritter Moore, ISBN 0443071454, 5:th ed., Churchill Livingstone 2003 Page 138. v d e Ion channel, receptor: ligand-gated ion channels Cys-loop receptors 5-HT/serotonin 5-HT3 A, B, C, D, E GABA GABA A α1, α2, α3, α4, α5, α6, β1, β2, β3, γ1, γ2, γ3, δ, ε, Ï€, θ GABA C Ï?1, Ï?2, Ï?3 Glycine α1, α2, α3, α4, β Nicotinic acetylcholine monomers: α1, α2, α3, α4, α5, α6, α7, α9, α10, β1, β2, β3, β4, δ, ε pentamers: α42β23, α75, α12β43 - Ganglion type, α12β1δε - Muscle type Ionotropic glutamates AMPA 1, 2, 3, 4 Kainate 1, 2, 3, 4, 5 NMDA 1, 2A, 2B, 2C, 2D, 3A, 3B, L1A, L1B ATP-gated channels Purinergic receptors: P2X 1, 2, 3, 4, 5, 6, 7 Retrieved from http://en..org/wiki/Alpha-4_beta-2_nicotinic_receptor Categories: Receptors Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 2 June 2008, at 07:03

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