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20-September-2008 09:55:47 - Aquaretics An aquaretic is a class of drug that is used to promote aquaresis. They are not strictly speaking diuretics, but are sometimes classified as such. Herbal aquaretics include adonis, agrimony, bearberry, buchu, dandelion, heartsease, hydrangea, lady's mantle, larch, and sassafras. These increase blood flow to the kidneys without increasing sodium and chloride resorption, thus causing an increase in urine whilst retaining electrolytes. However, the increase in intravascular fluid volume that they cause translates into an increase vascular resistance, and higher blood pressure.1 Synthetic aquaretics, a new class of drug, are V2 receptor antagonists, such as OPC-31260. These have been used in clinical trials as a treatment for Syndrome of inappropriate antidiuretic hormone SIADH.23 Tablets This pharmacology-related article is a stub. References ^ Lucinda G. Miller and Wallace J. Murray 1998. Herbal Medicinals: A Clinician's Guide. Haworth Press, 147. ISBN 0789004666. ^ Toshikazu Saito, San-e Ishikawa, Keishi Abe, Kyuzi Kamoi, Kenichi Yamada, Kurakazu Shimizu, Takao Saruta and Sho Yoshida April 1997. Acute Aquaresis by the Nonpeptide Arginine Vasopressin AVP Antagonist OPC-31260 Improves Hyponatremia in Patients with Syndrome of Inappropriate Secretion of Antidiuretic Hormone SIADH. The Journal of Clinical Endocrinology Metabolism 82 4: 1054-1057. The Endocrine Society. PMID 9100572. ^ D. A. Warrell, Timothy M. Cox, and John D. Firth 2003. Oxford Textbook of Medicine. Oxford University Press, 211-212. ISBN 0198569785. Retrieved from http://en..org/wiki/Aquaretics Categories: Pharmacology stubs | Medicinal plants | Diuretics Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 17 July 2008, at 15:29
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