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News About Biological_activity

20-September-2008 09:55:59 - activity Pharmacological or biological activity is an expression describing the beneficial or adverse effects of a drug on living matter. When the drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or pharmacophore but can be modified by the other constituents. The main kind of biological activity is a substance's toxicity. Activity is generally dosage-dependent and it is not uncommon to have effects ranging from beneficial to adverse for one substance when going from low to high doses. Activity depends critically on fulfillment of the ADME criteria. Whereas a material is considered bioactive if it has interaction with or effect on any cell tissue in the human body, pharmacological activity is usually taken to describe beneficial effects, i.e. the effects of drug candidates. In the study of biomineralisation, bioactivity is often meant as the formation of calcium phosphate deposits on the surface of objects placed in simulated body fluid, a buffer solution with ion content similar to blood. See also Lipinski's Rule of Five, describing molecular properties of drugs QSAR, quantitative structure-affinity relationship Chemical property Molecular property Physical property Chemical structure Tablets This pharmacology-related article is a stub. Retrieved from http://en..org/wiki/Biological_activity Categories: Pharmacology stubs | Pharmacodynamics Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages 日本語 Polski This page was last modified on 5 March 2008, at 21:14

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