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20-September-2008 09:55:47 - Coma For other uses, see Coma disambiguation. Symptom/Sign: Coma Classifications and external resources ICD-10 R40.2 ICD-9 780.01 In medicine, a coma from the Greek κῶμα koma, meaning deep sleep is a profound state of unconsciousness. A comatose person cannot be awakened, fails to respond normally to pain or light, does not have sleep-wake cycles, and does not take voluntary actions. Coma may result from a variety of conditions, including intoxication, metabolic abnormalities, central nervous system diseases, acute neurologic injuries such as stroke, and hypoxia. A coma may also result from head trauma caused by mechanisms such as falls or car accidents. It may also be deliberately induced by pharmaceutical agents in order to preserve higher brain function following another form of brain trauma, or to save the patient from extreme pain during healing of injuries or diseases. The underlying cause of the coma is bilateral damage to the Reticular formation of the midbrain, which is important in regulating sleep.1 Contents 1 Severity 2 Outcome 3 See also 4 References 5 External links Severity The severity of coma impairment is categorized into several levels. Patients may or may not progress through these levels. In the first level, the brain responsiveness lessens, normal reflexes are lost, the patient no longer responds to pain and cannot hear. Contrary to popular belief, a person in a coma does not always lie still and quiet. They may move, talk, and perform other functions that may sometimes appear to be conscious acts but are not.2 Two scales of measurement often used in Traumatic Brain Injury TBI diagnosis to determine the level of coma are the Glasgow Coma Scale GCS and the Ranchos Los Amigos Scale RLAS. The GCS is a simple 3 to 15-point scale 3 being the worst and 15 being that of a normal person used by medical professionals to assess severity of neurologic trauma, and establish a prognosis. The RLAS is a more complex scale that has eight separate levels, and is often used in the first few weeks or months of coma while the patient is under closer observation, and when shifts between levels are more frequent. Outcome Outcomes range from recovery to death. Comas generally last a few days to a few weeks. They rarely last more than 2 to 5 weeks but some have lasted as long as several years. After this time, some patients gradually come out of the coma, some progress to a vegetative state, and others die. Some patients who have entered a vegetative state go on to regain a degree of awareness. Others remain in a vegetative state for years or even decades the longest recorded period being 37 years.3 The outcome for coma and vegetative state depends on the cause, location, severity and extent of neurological damage. A deeper coma alone does not necessarily mean a slimmer chance of recovery, because some people in deep coma recover well while others in a so-called milder coma sometimes fail to improve. People may emerge from a coma with a combination of physical, intellectual and psychological difficulties that need special attention. Recovery usually occurs gradually - patients acquire more and more ability to respond. Some patients never progress beyond very basic responses, but many recover full awareness. Regaining consciousness is not instant: in the first days, patients are only awake for a few minutes, and duration of time awake gradually increases. Predicted chances of recovery are variable owing to different techniques used to measure the extent of neurological damage. All the predictions are based on statistical rates with some level of chance for recovery present: a person with a low chance of recovery may still awaken. Time is the best general predictor of a chance of recovery: after 4 months of coma caused by brain damage, the chance of partial recovery is less than 15%, and the chance of full recovery is very low.45 The most common cause of death for a person in a vegetative state is secondary infection such as pneumonia which can occur in patients who lie still for extended periods. Occasionally people come out of coma after long periods of time. After 19 years in a minimally conscious state, Terry Wallis spontaneously began speaking and regained awareness of his surroundings.6 A brain-damaged man, trapped in a coma-like state for six years, was brought back to consciousness in 2003 by doctors who planted electrodes deep inside his brain. The method, called deep-brain electrical stimulation DBS successfully roused communication, complex movement and eating ability in the 38-year-old American man who suffered a traumatic brain injury. His injuries left him in a minimally conscious state MCS, a condition akin to a coma but characterized by occasional, but brief, evidence of environmental and self-awareness that coma patients lack.7 See also Persistent vegetative state vegetative coma, deep coma without detectable awareness Brain death irreversible coma, irreversible end of all brain activity Process Oriented Coma Work, for an approach to working with residual consciousness in comatose patients Level of consciousness References Sources consulted BIAUSA Brain Injury Association of America, Types of Brain Injury. NINDS National Institute of Neurological Diseases and Stroke, public domain information on TBI NINDS National Institute of Neurological Diseases and Stroke, public domain information on coma Endnotes ^ The Human Brain: an introduction to its functional anatomy 5th ed by J Nolte chpt 11 pp262-290 ^ BBC NEWS | Europe | Pole wakes up from 19-year coma ^ According to the Guinness Book of Records, the longest period spent in coma was by Elaine Esposito. She did not wake up after being anaesthetized for an appendectomy on August 6, 1941, at age 6. She died on November 25, 1978 at age 43 years 357 days, having been in a coma for 37 years 111 days. ^ Clinical predictors and neuropsychological outcome...Acta Neurochir Wien. 2004 - PubMed Result ^ brain injury .com | Coma traumatic brain injury - Brain Injury Coma ^ Mother stunned by coma victim's unexpected words - smh.com.au ^ Electrodes stir man from six-year coma-like state, Cosmos Magazine 2 August 2007. External links Brain Injury Fact Sheets - Information on coma, and many other effects of brain injury. TBI Resource Guide Central source of information, services and products relating to brain injury, brain injury recovery, and post-acute rehabilitation. Headway - the brain injury association UK based charity providing information and support v d e Symptoms and signs: cognition, perception, emotional state and behaviour R40-R46, 780-781 General Anxiety - Somnolence - Coma - Amnesia Anterograde amnesia, Retrograde amnesia - Dizziness/Vertigo Olfaction Anosmia - Hyposmia - Dysosmia - Parosmia - Hyperosmia Taste Ageusia - Hypogeusia - Dysgeusia - Parageusia - Hypergeusia Retrieved from http://en..org/wiki/Coma Categories: Neurology | Intensive care medicine | Emergency medicine | Central nervous system Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Asturianu Bosanski БългарÑ?ки Dansk Deutsch Eesti Español Esperanto Français Hrvatski Bahasa Indonesia Italiano עברית ქáƒ?რთული LatvieÅ¡u Lietuvių Nederlands 日本語 ‪Norsk bokmÃ¥l‬ Polski Português РуÑ?Ñ?кий Simple English SlovenÄ?ina СрпÑ?ки / Srpski Suomi Svenska ä¸æ–‡ This page was last modified on 30 July 2008, at 11:20
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