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20-September-2008 09:55:47 - Competitive antagonist A competitive antagonist is a receptor antagonist that binds to a receptor but does not activate the receptor. The antagonist will compete with available agonist for receptor binding sites on the same receptor. Sufficient antagonist will displace the agonist from the binding sites, resulting in a lower frequency of receptor activation. Presence of a competitive antagonist will shift an agonism dose-response curve to the right.1 A Schild plot for a competitive antagonist will have a slope equal to 1, and the X-intercept and Y-intercept will each equal the dissociation constant of the antagonist.1 A competitive antagonist can be reversible competitive antagonist or irreversible competitive antagonist. References ^ a b Doseresponse curves in the presence of antagonists Tablets This pharmacology-related article is a stub. Retrieved from http://en..org/wiki/Competitive_antagonist Categories: Pharmacology | Pharmacology stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch This page was last modified on 9 August 2008, at 15:34
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