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20-September-2008 09:55:52 - Decay accelerating factor Redirected from Cromer antigen system CD55 molecule, decay accelerating factor for complement Cromer blood group PDB rendering based on 1h03. Available structures: 1h03, 1h04, 1h2p, 1h2q, 1m11, 1nwv, 1ojv, 1ojw, 1ojy, 1ok1, 1ok2, 1ok3, 1ok9, 1uot, 1upn, 2c8i Identifiers Symbols CD55; CR; DAF; TC External IDs OMIM: 125240 MGI: 104850 HomoloGene: 479 Gene ontology Molecular function: GPI anchor binding Cellular component: soluble fraction integral to plasma membrane membrane Biological process: complement activation, classical pathway innate immune response RNA expression pattern More reference expression data Orthologs Human Mouse Entrez 1604 13136 Ensembl ENSG00000196352 ENSMUSG00000026399 Uniprot P08174 Q3TU32 Refseq NM_000574 mRNA NP_000565 protein NM_010016 mRNA NP_034146 protein Location Chr 1: 205.56 - 205.6 Mb Chr 1: 132.27 - 132.29 Mb Pubmed search 1 2 Decay accelerating factor CD55 is a 70 kDa membrane protein that regulates the complement system on the cell surface. It prevents the assembly of the C3bBb complex the C3-convertase of the alternative pathway or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex. This glycoprotein is broadly distributed among hematopoietic and non-hematopoietic cells. It is a determinant for the Cromer blood group system. Contents 1 Pathology 2 See also 3 Further reading 4 External links Pathology DAF is not expressed on paroxysmal nocturnal hemoglobinuria III markedly abnormal RBCs; however, this deficiency is not the cause of PNH. See also List of human clusters of differentiation Further reading Selinka HC, Wolde A, Sauter M, et al. 2004. Virus-receptor interactions of coxsackie B viruses and their putative influence on cardiotropism.. Med. Microbiol. Immunol. 193 2-3: 127-31. doi:10.1007/s00430-003-0193-y. PMID 12920584. Mikesch JH, Schier K, Roetger A, et al. 2007. The expression and action of decay-accelerating factor CD55 in human malignancies and cancer therapy.. Cell. Oncol. 28 5-6: 223-32. PMID 17167176. External links MeSH Decay-Accelerating+Factor Cromer blood group system at BGMUT, Blood Group Antigen Gene Mutation Database at NCBI, NIH v d e Proteins: complement system C, L, A Activators CLA: C3-convertase - C5-convertase - MAC C6, C7, C8, C9 - L: Mannan-binding lectin - A: Factor P/Properdin Enzymes C: C1Q/C1R/C1S - C4 C4a - C2 - CLA: C3 C3a, C3b/iC3b - C5 C5a - L: MASP1 - MASP2 - A: Complement factor B - Factor D Inhibitors CLA: C1-inhibitor - Decay accelerating factor - Factor I - CL: C4BP - A: Factor H Complement receptors CR1 - CR2 - CR3 - CR4 - CD11b/CD11c/CD18 - Anaphylatoxin C3a, C5a v d e Proteins: clusters of differentiation see also list of human clusters of differentiation 1-50 CD1 a-c, 1A, 1D, 1E - CD2 - CD3 γ, δ, ε - CD4 - CD5 - CD6 - CD7 - CD8 a - CD9 - CD10 - CD11 a, b, c - CD13 - CD14 - CD15 - CD16 A, B - CD18 - CD19 - CD20 - CD21 - CD22 - CD23 - CD24 - CD25 - CD26 - CD27 - CD28 - CD29 - CD30 - CD31 - CD32 A, B - CD33 - CD34 - CD35 - CD36 - CD37 - CD38 - CD39 - CD40 - CD41- CD42 a, b, c, d - CD43 - CD44 - CD45 - CD46 - CD47 - CD48 - CD49 a, b, c, d, e, f - CD50 51-100 CD51 - CD52 - CD53 - CD54 - CD55 - CD56 - CD57- CD58 - CD59 - CD61 - CD62 E, L, P - CD63 - CD64 - CD66 a, b, c, d, e, f - CD68 - CD69 - CD70 - CD71 - CD72 - CD73 - CD74 - CD79 a, b - CD80 - CD81 - CD82 - CD83 - CD84 - CD85 a, d, e, h, j, k - CD86 - CD87 - CD88 - CD89 - CD90 - CD91- CD92 - CD93 - CD94 - CD95 - CD97 - CD98 - CD99 - CD100 101-150 CD101 - CD102 - CD103 - CD104 - CD105 - CD106 - CD107 a, b - CD108 - CD109 - CD110 - CD111 - CD112 - CD113 - CD114 - CD115 - CD116 - CD117 - CD118 - CD119 - CD120 a, b - CD121 a, b - CD122 - CD123 - CD124 - CD125 - CD126 - CD127 - CD129 - CD130 - CD131 - CD132 - CD133 - CD134 - CD135 - CD136 - CD137 - CD138 - CD140b - CD141 - CD142 - CD143 - CD144 - CD146 - CD147 - CD148 - CD150 151-200 CD151 - CD152 - CD153 - CD154 - CD155 - CD156 a, b, c - CD157 - CD158 a, d, e, i, k - CD159 a, c - CD160 - CD161 - CD162 - CD163 - CD164 - CD166 - CD167 a, b - CD168 - CD169 - CD170 - CD171 - CD172 a, b, g - CD174 - CD177 - CD178 - CD179 a, b - CD181 - CD182 - CD183 - CD184 - CD185 - CD186 - CD191 - CD192 - CD193 - CD194 - CD195 - CD196 - CD197 - CDw198 - CDw199 - CD200 201-250 CD201 - CD202b - CD204 - CD205 - CD206 - CD207 - CD208 - CD209 - CDw210 a, b - CD212 - CD213a 1, 2 - CD217 - CD218 a, b - CD220 - CD221 - CD222 - CD223 - CD224 - CD225 - CD226 - CD227 - CD228 - CD229 - CD230 - CD233 - CD234 - CD235 a, b - CD236 - CD238 - CD239 - CD240CE - CD241 - CD243 - CD244 - CD246 - CD247- CD248 - CD249 251-300 CD252 - CD253 - CD254 - CD256 - CD257 - CD258 - CD261 - CD262 - CD264 - CD265 - CD266 - CD267 - CD268 - CD269 - CD271 - CD272 - CD273 - CD274 - CD275 - CD276 - CD278 - CD279 - CD280 - CD281 - CD282 - CD283 - CD284 - CD286 - CD288 - CD289 - CD290 - CD292 - CDw293 - CD294 - CD295 - CD297 - CD298 - CD299 301-350 CD300A - CD304 - CD305 - CD307 - CD309 - CD312 - CD314 - CD315 - CD316 - CD317 - CD318 - CD320 - CD321 - CD322 - CD324 - CD325 - CD326 - CD328 - CD329 - CD331 - CD332 - CD333 - CD334 - CD335 - CD336 - CD337 - CD338 - CD339 - CD340 - CD344 - CD349 - CD350 This biochemistry article is a stub. This immunology article is a stub. Retrieved from http://en..org/wiki/Decay_accelerating_factor Categories: Genes on chromosome 1 | Human proteins | Blood | Transfusion medicine | Hematology | Blood antigen systems | Biochemistry stubs | Immunology stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 8 July 2008, at 02:56
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