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20-September-2008 09:55:48 - Descending limb of loop of Henle Descending limb of loop of Henle Scheme of renal tubule and its vascular supply. Labeled at center left. Nephron. Diagram is labeled in Polish, but ion flow can still be identified. Gray's subject #253 1223 Dorlands/Elsevier l_10/12493919 The descending limb of loop of Henle is the portion of the renal tubule constituting the first part of the loop of Henle. Contents 1 Physiology 2 Histology 3 Nomenclature 4 Additional images 5 References Physiology The permeability is as follows: Substance Permeability ions Low permeability. Sodium and chloride ions do not easily pass through. 1 urea Moderate permeability.2 water Highly permeable. Water is readily reabsorbed from the descending limb by osmosis.3 Also, the medullary interstitium is highly concentrated because of the activity of the ascending limb, leading to a strong osmotic gradient from the descending limb to the medulla. Because of these factors, the concentration of the urine increases dramatically in the descending limb. Osmolality can reach up to 1400 mOsmol/kg by the end of the descending limb.3 Histology The epithelium is low simple cuboidal.4 They can be distinguished from the vasa recta by the absence of blood, and they can be distinguished from the thick ascending limb by the thickness of the epithelium.5 Nomenclature Like the ascending limb, the descending limb has thick and thin portions. However, this distinction is not as important physiologically as in the ascending limb, so often the two are treated as one structure. The thick descending limb is less important than the thin descending limb, so often the terms descending limb and thin descending limb are used interchangeably. Some sources simply refer to a thin limb. In this context, the thin ascending limb of loop of Henle would be included. Additional images Longitudinal section of descending limb of Henle's loop. a. Membrana propria. b. Epithelium. References ^ a.The descending limb of the loop of Henle is highly permeable to water and relatively impermeable to solutes such as Na and Cl ^ Physiology at MCG 7/7ch08/7ch08p09 ^ a b Physiology at MCG 7/7ch07/7ch07p09 ^ Organology at UC Davis Urinary/mammal/medulla/medulla1 - Mammal, kidney medulla LM, Medium ^ Histology at BU 15804loa This article was originally based on an entry from a public domain ion of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please the article if this is the case, and feel free to remove this notice when it is no longer relevant. This anatomy article is a stub. v d e Urinary system - Kidney Layers Renal fascia Renal capsule Renal cortex Renal column Renal medulla Renal sinus, Renal pyramids, medullary interstitium Renal lobe Cortical lobule Medullary ray Nephron Afferent circulation Renal artery → Segmental arteries → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Renal corpuscle Glomerulus, Bowman's capsule Renal tubule Proximal tubule → Loop of Henle Descending, Thin ascending, Thick ascending → Distal convoluted tubule → Connecting tubule → Collecting ducts → Duct of Bellini → Renal papilla → Minor calyx → Major calyx → Renal pelvis → Ureter Efferent circulation Glomerulus → Efferent arterioles → Peritubular capillaries / Vasa recta → Arcuate vein → Interlobar veins → Renal vein Juxtaglomerular apparatus Macula densa Juxtaglomerular cells Mesangium/Extraglomerular mesangial cell Filtration Glomerular basement membrane Podocyte Filtration slits Mesangium/Intraglomerular mesangial cell Tubular fluid Renal physiology Acid base physiology Fluid balance Retrieved from http://en..org/wiki/Descending_limb_of_loop_of_Henle Categories: Anatomy stubs | Kidney Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages 日本語 This page was last modified on 11 August 2008, at 19:5
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