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20-September-2008 09:55:50 - Dihydrexidine Dihydrexidine Systematic IUPAC name 5,6,6a,7,8,12b-hexahydro- benzoaphenanthridine-10,11-diol Identifiers CAS number ? ATC code ? PubChem 5311070 Chemical data Formula C17H17NO2 Mol. mass 267.322 Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Dihydrexidine is a synthetic compound that acts as a dopamine D1/D5 receptor agonist. It was found to have ten-fold selectivity for the D1 versus the D2 receptor. It has been suggested that it causes agonist-typical functional changes. It showed unique functional selectivity at D2L receptors in situ and in vitro. Reference: Novel Mechanisms of Drug Action: Funcitonal Slectivity at D2 Dopamine Receptors A lesson for Drug Discovery Richard B. Mailman and Elaine A. Gay This molecular or cell biology article is a stub. Tablets This pharmacology-related article is a stub. v d e Anti-parkinson drugs: dopaminergic agents N04B Dopa and derivatives Droxidopa Levodopa Melevodopa Etilevodopa Adamantane derivatives Amantadine Dopamine agonists A-412,997 Apomorphine Bromocriptine Cabergoline Dihydrexidine Dihydroergocryptine mesylate Fenoldopam Lisuride Pergolide Piribedil Pramipexole Propylnorapomorphine Quinpirole Ropinirole Rotigotine SKF 38393 SKF 82958 MAOIs B Selegiline Rasagiline COMT inhibitors Entacapone Tolcapone Other Budipine dopa decarboxylase inhibitor Carbidopa Retrieved from http://en..org/wiki/Dihydrexidine Categories: Molecular and cellular biology stubs | Pharmacology stubs | Heterocyclic compounds 4 or more rings | Dopamine agonists Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 19 August 2008, at 15:50
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