Sierra Acai Company
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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:55:50 - Entacapone Entacapone Systematic IUPAC name 2E-2-cyano-3-3,4-dihydroxy-5-nitrophenyl-N,N-diethylprop-2-enamide Identifiers CAS number 130929-57-6 ATC code N04BX02 PubChem 5281081 DrugBank APRD00416 Chemical data Formula C14H15N3O5 Mol. mass 305.286 g/mol Synonyms E-a-cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide E-2-cyano-N,N-diethyl-3-3,4-dihydroxy-5-nitrophenylacrylamide Pharmacokinetic data Bioavailability 35% Protein binding 98% binds to serum albumin Metabolism Hepatic Half life 0.4-0.7 hour Excretion 90% feces, 10% urine Therapeutic considerations Pregnancy cat. CUS Legal status Prescription only, unscheduled USA Routes Oral Entacapone INN pronounced /ˌɛntəkəˈpoʊn/, /ɛnˈtækəpoʊn/ is a catechol-O-methyl transferase inhibitor for the treatment of Parkinson's disease. When administered in conjunction with dopaminergic agents such as L-DOPA, entacapone increases the bioavailability of these compounds by facilitating their passage across the blood-brain barrier. It is a member of the class of nitrocatechols. The most frequent undesirable effects caused by entacapone relate to the increased effects of L-DOPA, such as involuntary movements dyskinesias.These occur most frequently at the beginning of entacapone treatment. Others common side effects are gastrointestinal problems, including diarrhoea, nausea and abdominal pains. The substance may cause urine to turn reddish-brown. This is a harmless side effect and is not a cause for concern. In studies with entacapone, some people have reported experiencing a dry mouth. Entacapone is developed by Orion Pharma and marketed by Novartis under the trade names Comtan and Stalevo in the United States. Stalevo is a medication that contains carbidopa, levodopa active ingredients in Sinemet, and entacapone active ingredient in Comtan. External links 1 fda website Comtan manufacturer's website Stalevo manufacturer's website v d e Anti-parkinson drugs: dopaminergic agents N04B Dopa and derivatives Droxidopa Levodopa Melevodopa Etilevodopa Adamantane derivatives Amantadine Dopamine agonists A-412,997 Apomorphine Bromocriptine Cabergoline Dihydrexidine Dihydroergocryptine mesylate Fenoldopam Lisuride Pergolide Piribedil Pramipexole Propylnorapomorphine Quinpirole Ropinirole Rotigotine SKF 38393 SKF 82958 MAOIs B Selegiline Rasagiline COMT inhibitors Entacapone Tolcapone Other Budipine dopa decarboxylase inhibitor Carbidopa Retrieved from http://en..org/wiki/Entacapone Categories: Antiparkinsonian agents | COMT inhibitors Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Suomi 日本語 中文 This page was last modified on 3 July 2008, at 13:16
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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