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20-September-2008 09:55:48 - Fertility medication Fertility medication is medication that enhances fertility. For women, fertility medication is used to stimulate follicle development of the ovary. For males, on the other hand, there is a very sparse arsenal of fertility medication. Agents that enhance ovarian activity can be classified as either Gonadotropin releasing hormone, Estrogen antagonists or Gonadotropins. Contents 1 Female 1.1 Gonadotropin releasing hormone 1.2 Estrogen antagonists 1.2.1 Clomiphene citrate 1.2.2 Aromatase inhibitors 1.3 Gonadotropins 1.3.1 Menotropins 1.3.2 Recombinant gonadotropins 1.4 Human chorionic gonadotropin 1.5 Other 2 Male 3 Adverse effects 4 See also 5 References Female Gonadotropin releasing hormone Main article: Gonadotropin-releasing hormone Either Gonadotropin releasing hormone GnRH itself or any of its agonist may be used. GnRH releases gonadotropins from the hypothalamus in the body. GnRH agonists includes i.e. Lupron. Estrogen antagonists Fertility medication inhibiting the effects of estrogen includes Clomiphene citrate and Aromatase inhibitors. Clomiphene citrate Main article: Clomiphene citrate Clomiphene citrate is a SERM. It inhibits the negative feedback of estrogen and therefore stimulates ovulation. Aromatase inhibitors Main article: Aromatase inhibitor Although primarily a breast cancer treatment, aromatase inhibitors can also work as fertility medication, probably by a mechanism similar to clomiphene citrate. Gonadotropins Gonadotropins are the hormones in the body that normally stimulate the gonads testes and ovaries. For medication, they can be extracted from urine or by genetic modification. Menotropins Main article: Menotropins Menotropins are urinary gonadotropins, i.e. they are extracted from the urine. Recombinant gonadotropins Recombinant gonadotropins are gonadotropins created by inserting the DNA coding it into bacteriae. The bacterial DNA is then called Recombinant DNA. Examples of recombinant FSH are Follistim and Gonal F, while Luveris is a recombinant LH. Human chorionic gonadotropin Main article: Human chorionic gonadotropin#Use as medication Human chorionic gonadotropin hCG is normally produced during pregnancy. However, it can also replace LH as a fertility medication. Other hMG is a medication containing FSH. Male There is no effective medication to treat oligospermia, so other assisted reproductive technology need to be used. Adverse effects Estrogen antagonists and gonadotropins may stimulate multiple follicles and other ovarian hormones leading to multiple birth and possible ovarian hyperstimulation syndrome. See also Manufacturers: Ferring Pharmaceuticals Organon International EMD Serono References v d e Major drug groups Gastrointestinal tract/metabolism A stomach acid Antacids, H2 antagonists, Proton pump inhibitors Antiemetics Laxatives Antidiarrhoeals/Antipropulsives Anti-obesity drugs Anti-diabetics Vitamins Dietary minerals Blood and blood forming organs B Antithrombotics Anticoagulants, Antiplatelets, Thrombolytics Antihemorrhagics Cardiovascular system C cardiac therapy/antianginals Cardiac glycosides, Antiarrhythmics, Cardiac stimulant Antihypertensives Diuretics Vasodilators Beta blockers renin-angiotensin system ACE inhibitors, Angiotensin II receptor antagonists, Renin inhibitors Antihyperlipidemics Skin D Emollients Cicatrizant Antipruritics Reproductive system G Hormonal contraception Fertility agents SERMs Sex hormones Endocrine system H Corticosteroids Sex hormones Thyroid hormones Antithyroid agent Infections and infestations J, P Antibiotics Antivirals Vaccines Antifungals Antiparasitic Antiprotozoals, Anthelmintics Malignant and immune disease L Anticancer agents Immunostimulators Immunosuppressants Muscles, bones, and joints M Anabolic steroids Anti-inflammatories NSAID Antirheumatics Corticosteroids Muscle relaxants Brain and nervous system N Anesthetics General, Local Analgesics Anticonvulsants Mood stabilizers Psycholeptic Anxiolytics, Antipsychotics, Hypnotics/Sedatives Psychoanaleptic Antidepressants, Stimulants/Psychostimulants Respiratory system R Bronchodilators Decongestants H1 antagonists Other ATC V Antidotes Contrast media Radiopharmaceuticals Dressing Retrieved from http://en..org/wiki/Fertility_medication Categories: Fertility medicine | Drugs | Hormonal agents Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Français This page was last modified on 3 August 2008, at 03:41
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