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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:55:57 - Ketotifen Ketotifen Systematic IUPAC name 4,9-dihydro-4-1-methyl-4-piperidinylidene- 10H-benzocyclohepta1,2-bthiopen-10-one Identifiers CAS number 34580-14-8 ATC code R06AX17 S01GX08 PubChem 3827 DrugBank APRD01061 Chemical data Formula C19H19NOS Mol. mass 309.426 g/mol Pharmacokinetic data Bioavailability 60% Protein binding 75% Metabolism Hepatic Half life 12 Hours Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status OTCUS Routes Oral, Eye Drops Ketotifen fumarate ophthalmic solutions marketed under the brand name Zaditor Novartis and Alaway Bausch and Lomb is an H1-antihistamine/mast cell stabilizer available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies. In its oral form, it is used to prevent asthma attacks. Side effects include drowsiness, weight gain, dry mouth, irritability, and increased nosebleeds. General Information Ketotifen relieves and prevents eye itchiness and/or irritation associated with most seasonal allergies. It starts working within minutes after administering the drops. The drug has not been studied in children under 3. Accidental ingestion of an entire bottle of ketotifen is unlikely to cause side effects since it contains less than 2 mg of medicine. The mean elimination half life is 12 hours.1 References ^ Grahnén A; Lönnebo A, Beck O, Eckernäs SA, Dahlström B, Lindström B May 1992. Pharmacokinetics of ketotifen after oral administration to healthy male subjects. Biopharm Drug Dispos 13 4: 255-62. doi:10.1002/bdd.2510130404. PMID 1600111. External links Zaditor web site Alaway web site v d e Histamine antagonists H1 or non-selective Alkylamines Bepotastine Bamipine Brompheniramine Chlorpheniramine Dexbrompheniramine Dexchlorpheniramine Dimethindene Metron S Pheniramine Pyrrobutamine Talastine Thenaldine Tolpropamine Triprolidine Ethanolamines Aminoalkyl ethers Bietanautine Bromazine/Bromodiphenhydramine Carbinoxamine Chlorphenoxamine Clemastine Diphenylpyraline Diphenhydramine Doxylamine Embramine p-Methyldiphenhydramine Moxastine Orphenadrine Phenyltoloxamine Setastine Ethylenediamines Chloropyramine Chlorothen Histapyrrodine Methafurylene Mepyramine Methapyrilene Pyrilamine Talastine Thenyldiamine Thonzylamine Tripelennamine Pyribenzamine Phenothiazine Tricyclics Ahistan Etymemazine Hydroxyethylpromethazine Isopromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine Thiazinamium Other Tricyclics Azatadine Clobenzepam Cyproheptadine Deptropine Isothipendyl Loratidine Piperazine Buclizine Chlorcyclizine Cinnarizine Clocinizine Hydroxyzine Niaprazine Oxatomide Benzhydryl compounds Cyclizine, Meclizine Others including selective, 2nd gen, 3rd gen Antazoline Astemizole Azatadine Azelastine Bepottastine Bamipine Cetoxine Clemizole Clobenztropine Deptropine Desloratadine Dimebon Ebastine Emedastine Epinastine Ketotifen Levocabastine Loratadine Mebhydrolin Mizolastine Phenindamine Pimethixene Pyrrobutamine Rupatadine Thenalidine Tritoqualine Alkylamine Acrivastine Tricyclic Olopatadine Piperazine Levocetirizine, Cetirizine Benzhydryl compounds Fexofenadine, Terfenadine H2 Cimetidine Famotidine Ranitidine Roxatidine Lafutidine Niperotidine Nizatidine H3 A-349,821 ABT-239 Burimamide Ciproxifan Clobenpropit Conessine Impentamine Iodophenpropit Thioperamide VUF-5681 H4 JNJ 7777120 Thioperamide VUF-6002 Tablets This pharmacology-related article is a stub. Retrieved from http://en..org/wiki/Ketotifen Categories: Antihistamines | H1 receptor antagonists | Pharmacology stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages БългарÑ?ки Italiano Polski ไทย This page was last modified on 3 July 2008, at 15:18
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