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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:55:56 - Mazindol Mazindol Systematic IUPAC name ? Identifiers CAS number 22232-71-9 ATC code A08AA05 PubChem 4020 DrugBank APRD01085 Chemical data Formula C16H13ClN2O Mol. mass 284.74 g/mol Pharmacokinetic data Bioavailability 93% Metabolism Hepatic Half life 10-13 hours Excretion Renal Therapeutic considerations Pregnancy cat. ? Legal status Schedule IVUS Schedule IV International Routes Oral Mazindol is a central nervous system stimulant. It is a tricyclic compound not to be confused with tricyclic antidepressants. It is marketed under the brand names Mazanor and Sanorex. Contents 1 Indications 2 Pharmacology 3 Mechanism of Action 4 Overdose 5 See also Indications Mazindol is used in short-term i.e., a few weeks treatment of exogenous obesity, in combination with a regimen of weight reduction based on caloric restriction, exercise, and behavior modification in patients with a body mass index of 30 kg of body weight per height in meters squared kg/m2, or in patients with a body mass index of 27 kg/m2 in the presence of risk factors such as hypertension, diabetes, or hyperlipidemia. Pharmacology Mazindol is a sympathomimetic amine, which is similar to amphetamine. It stimulates the central nervous system, which increases heart rate and blood pressure, and decreases appetite. Sympathomimetic anoretics appetite suppressants are used in the short-term treatment of obesity. Their appetite-reducing effect tends to decrease after a few weeks of treatment. Because of this, these medicines are useful only during the first few weeks of a weight-loss program. Mechanism of Action Although the mechanism of action of the sympathomimetics in the treatment of obesity is not fully known, these medications have pharmacological effects similar to those of amphetamines. Like other sympathomimetic appetite suppressants such as phentermine, mazindol is thought to act as a reuptake inhibitor of norepinephrine. Frame Overdose Symptoms of a mazindol overdose include: restlessness, tremor, rapid breathing, confusion, hallucinations, panic, aggressiveness, nausea, vomiting, diarrhea, an irregular heartbeat, and seizures. See also Norepinephrine reuptake inhibitor v d e Antiobesity preparations A08 -- see also anorectic Centrally acting Phentermine - Fenfluramine - Amfepramone - Dexfenfluramine - Mazindol - Cathine - Clobenzorex - Sibutramine - cannabinoids Rimonabant, Taranabant Peripherally acting Orlistat Retrieved from http://en..org/wiki/Mazindol Categories: Sympathomimetic amines Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages 日本語 Svenska Polski This page was last modified on 26 June 2008, at 02:5
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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