Sierra Acai Company
Sierra Acai Company
Open 7 Days a Week
MonaVie Independent Distributor
Distributor Training
Shop Online
Enroll Now
Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
Friends
Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:55:56 - Mesocarb Mesocarb Systematic IUPAC name 5-Phenylcarbamoylimino-3-1-phenylpropan-2-yl-5H-1,2,3-oxadiazol-3-ium-2-ide Identifiers CAS number 34262-84-5 ATC code ? PubChem 71932 Chemical data Formula C18H18N4O2 Mol. mass 322.36 g/mol Pharmacokinetic data Bioavailability ? Metabolism hepatic Half life ? Excretion renal Therapeutic considerations Pregnancy cat. ? Legal status Class C UK, Schedule III USA Routes Oral Mesocarb Sidnocarb, Sydnocarb is a stimulant drug which was developed in the USSR in the 1970s. 1 It has been shown to act as a dopamine reuptake inhibitor23 which is slower acting but longer lasting and less neurotoxic than dextroamphetamine.4 Mesocarb is still used for a variety of applications,5 including counteracting the sedative effects of benzodiazepine drugs,6 increasing workload capacity and cardiovascular function,7 treatment of ADHD and hyperactivity in children,89 as a nootropic,10 and as a drug to enhance resistance to extremely cold temperatures.1112 It is also listed as having antidepressant and anticonvulsant properties. Mesocarb is sold in Russia as 5 milligram tablets under the brand name Sydnocarb. Hydroxylated metabolites can be detected in urine for up to 10 days after consumption, reflecting a relatively long half-life.13 Mesocarb is almost unknown in the western world and is neither used in medicine or studied scientifically to any great extent outside Russia and other countries in the former Soviet Union. It has however been added to the list of drugs under international control and is illegal in most countries, despite its multiple therapeutic applications and the lack of significant abuse potential seen in clinical practice.14 Chemistry Mesocarb is a mesoionic sydnone imine. It has the amphetamine-backbone present, except that the RN has a complicated imine side-chain present. References ^ Anokhina IP, Zabrodin GD, Svirinovskii IaE. Characteristics of the central action of sidnocarb. Zhurnal Nevropatologii i Psikhiatrii Imeni S S Korsakova. 1974;744:594-602. Russian PMID 4825943 ^ Anderzhanova EA, Afanas'ev II, Kudrin VS, Rayevsky KS. Effect of d-amphetamine and sydnocarb on the extracellular level of dopamine, 3,4-dihydroxyphenylacetic acid, and hydroxyl radicals generation in rat striatum. Annals of the New York Academy of Sciences. 2000 Sep;914:137-45. PMID 11085316 ^ Gainetdinov RR, Sotnikova TD, Grekhova TV and Rayevsky KS. Effects of a psychostimulant drug Sydnocarb on rat brain dopaminergic transmission in vivo. European Journal of Pharmacology 1997 Dec 4;3401:53-8. PMID 9527506 ^ Afanas'ev II, Anderzhanova EA, Kudrin VS, Rayevsky KS. Effects of amphetamine and sydnocarb on dopamine release and free radical generation in rat striatum. Pharmacology, Biochemistry and Behavior. 2001 Jul-Aug;693-4:653-8. PMID 11509228 ^ Witkin JM, Savtchenko N, Mashkovsky M, Beekman M, Munzar P, Gasior M, Goldberg SR, Ungard JT, Kim J, Shippenberg T, Chefer V. Behavioral, toxic, and neurochemical effects of sydnocarb, a novel psychomotor stimulant: comparisons with methamphetamine. Journal of Pharmacology and Experimental Therapeutics. 1999 Mar;2883:1298-310. PMID 10027871 ^ Valueva LA and Tozhanova NM. Correction by Sydnocarb of side effects produced by tranquilizers of benzodiazepine series. Journal of Neurology, Neurosurgery and Psychiatry 1982; 9:92-97. ^ Vinar O, Klein DF, Potter WZ, Gause EM. A survey of psychotropic medications not available in the United States. Neuropsychopharmacology 1991;5:201 ^ Turova NF, Misionzhnik EIu, Ermolina LA, Aziavchik AV, Krasov VA. Excretion of monoamines, their precursors and metabolites in the hyperactivity syndrome in mentally defective children. Voprosy Msinskoi Khimii. 1988 Jan-Feb;341:47-50. Russian PMID 3369126 ^ Krasov VA. Sidnocarb treatment of young schoolchildren with the hyperdynamic syndrome. Zhurnal Nevropatologii i Psikhiatrii Imeni S S Korsakova. 1988;888:97-101. Russian PMID 3195293 ^ Ganiev MM, Kharlamov AN, Raevskii KS, Guseinov DIa. Effect of sidnocarb on learning and memory. Biulleten Eksperimental Biologii i Msiny. 1987 Oct;10410:453-4. Russian PMID 3676468 ^ Barer AS, Lakota NG, Ostrovskaia GZ, Shashkov VS. Pharmacologic correction of the effect of cold on man. Kosmicheskaia Biologiia i Aviakosmicheskaia Msina. 1988 Nov-Dec;226:66-73. Russian PMID 2906380 ^ Levina MN, Badyshtov BA, Gan'shina TS. Thermoprotector properties of a combination of sydnocarb with ladasten. Eksperimental'naia i Klinicheskaia Farmakologiia. 2006 Jan-Feb;691:71-3. Russian PMID 16579065 ^ Shpak AV, Appolonova SA, Semenov VA. Validation of liquid chromatography-electrospray ionization ion trap mass spectrometry method for the determination of mesocarb in human plasma and urine. Journal of Chromatographic Science. 2005 Jan;431:11-21. PMID 15808002 ^ Rudenko GM and Altshuler RA. Experimental and clinical study of Sydnocarb. Hung Pharmacotherapy, 1978;124:150-154 Russian v d e Stimulants Alkylamines Cyclopentamine Geranamine Isometheptene Octodrine Propylhexedrine Tuamine Alphapyrrolidinylalkiophenones α-PPP MDPPP MDPV MPBP MPHP MPPP MOPPP Pyrovalerone Cholinergics ABT-089 ABT-418 Anabasine Arecoline Cotinine Cytisine Dianicline Epibatidine Epiboxidine GTS-21 Ispronicline Nicotine Rivanicline Tebanicline Varenicline Convulsants Bicuculline DMCM Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil Carphedon Modafinil Phenethylamines 4-Bromomethcathinone 4-Fluoroamphetamine 4-Fluoromethamphetamine 4-Fluoromethcathinone 4-Methylmethcathinone 4-MTA Aletamine Amfepentorex Amphechloral Amphetamine Dextroamphetamine, Adderall Amphetaminil Benzphetamine Bupropion Cathinone Chlorphentermine Clenbuterol Clobenzorex Clortermine Diethylpropion Dimethoxyamphetamine Dimethylamphetamine Dimethylcathinone Ephedrine Epinephrine Ethcathinone Ethylamphetamine Fenethylline Fenfluramine Fenproporex Fludorex Furfenorex Levomethamphetamine Lisdexamfetamine MDMA Mefenorex Methamphetamine Methcathinone Methoxyphedrine Methylone Octopamine Ortetamine Parahydroxyamphetamine PCA PIA PMA PMEA PMMA PPAP Phendimetrazine Phenmetrazine Phentermine Phenylephrine Phenylpropanolamine Propylamphetamine Pseudoephedrine Selegiline Synephrine Tiflorex Xylopropamine Phenylaminooxazoles 4-Methyl-aminorex Aminorex Clominorex Fenozolone Fluminorex Pemoline Thozalinone Piperazines 2C-B-BZP BZP GBR-12783 GBR-12935 GBR-13069 GBR-13098 GBR-13119 MeOPP MBZP Vanoxerine Piperidines 2-Benzylpiperidine Desoxypipradrol Diphemethoxidine Ethylphenidate HDMP-28 --Methyl-1-methyl-4β-2-naphthylpiperidine-3β-carboxylate Methylphenidate Dexmethylphenidate Nocaine Phacetoperane Pipradrol Tropanes 3α-Bis-4-fluorophenylmethoxytropane 3α-4-Chlorophenylphenylmethoxytropane 3-Pseudotropyl-4-fluorobenzoate Altropane IACFT Brasofensine CFT WIN 35,428 β-CIT RTI-55 Cocaethylene Cocaine β-CPPIT Dichloropane RTI-111 Difluoropine FE-β-CPPIT FP-β-CPPIT PIT PTT RTI-31 RTI-32 RTI-51 RTI-112 RTI-113 RTI-121 IPCIT RTI-126 RTI-150 RTI-171 RTI-177 RTI-336 Tesofensine Troparil β-CPT, WIN 35,065-2 WF-23 WF-33 WF-60 Xanthines Aminophylline Caffeine Dimethazan Paraxanthine Theobromine Theophylline Others Amineptine Bemegride Benzydamine BPAP Bromantane BTQ Clofenciclan Cypenamine Cyprodenate Diclofensine Dimethocaine Diphenyl prolinol Ethamivan Fencamfamine Feprosidnine Gilutensin GYKI-52895 Hexacyclonate Indanorex Indatraline LR-5182 Mazindol Mesocarb Naphthylisopropylamine Nikethamide Nomifensine Phthalimidopropiophenone Prolintane Sibutramine Yohimbine Zylofuramine See also Sympathomimetic amines Retrieved from http://en..org/wiki/Mesocarb Categories: Stimulants | Dopamine reuptake inhibitors Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages РуÑ?Ñ?кий This page was last modified on 5 April 2008, at 03:1
39 Reasons to Drink Acai Juice Every Day
What is MonaVie - Watch the 8-minute video
Discovering MonaVie video
The Power of You video
Log into your Wholesale MonaVie Account
So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
1. Click on Enroll Now (30 - 55% off retail price)
2. Pay $39 for your Wholesale ID number.
3. NO minimum order required.
4. MonaVie is delivered to your door in 3 to 5 days.