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20-September-2008 09:55:58 - Mendelian Inheritance in Man Redirected from OMIM The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and-when possible-links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene. Contents 1 Versions 2 Collection process 3 The MIM code 4 See also 5 References 6 External links Versions It is available as a book named after the project, and it is currently in its 12th ion. The online version is called Online Mendelian Inheritance in Man OMIM, which can be accessed with the Entrez database searcher of the National Library of Medicine and is part of the NCBI project Education. Collection process The information in this database is collected and processed under the leadership of Dr. Victor A. McKusick at Johns Hopkins University, assisted by a team of science writers and ors. Relevant articles are identified, discussed and written up in the relevant entries in the MIM database. The MIM code Every disease and gene is assigned a six digit number of which the first number classifies the method of inheritance. If the initial digit is 1, the trait is deemed autosomal dominant; if 2, autosomal recessive; if 3, X-linked. Wherever a trait defined in this dictionary has a MIM number, the number from the 12th ion of MIM, is given in square brackets with or without an asterisk asterisks indicate that the mode of inheritance is known; a number symbol # before an entry number means that the phenotype can be caused by mutation in any of two or more genes as appropriate e.g., Pelizaeus-Merzbacher disease MIM169500 is a well-established, autosomal, dominant, mendelian disorder. First Digit Range of MIM codes Method of inheritance 1 100000-199999 Autosomal dominant loci or phenotypes created before May 15, 1994 2 200000-299999 Autosomal recessive loci or phenotypes created before May 15, 1994 3 300000-399999 X-linked loci or phenotypes 4 400000-499999 Y-linked loci or phenotypes 5 500000-599999 Mitochondrial loci or phenotypes 6 600000- Autosomal loci or phenotypes created after May 15, 1994 See also Medical classification Online Mendelian Inheritance in Animals Mouse Locus Catalogue Mendelian inheritance References Table from the OMIM FAQ McKusick, VA 1998. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders. Baltimore, Maryland: The Johns Hopkins University Press. ISBN 0-8018-5742-2. External links Online Mendelian Inheritance in Man to search OMIM v d e Databases supported by Bioinformatic Harvester NCBI-BLAST · CDD · Ensembl · Entrez · Flybase · Flymine · GFP-cDNA · Genome browser · GeneCard · Google Scholar · GoPubMed · HomoloGene · iHOP · IPI · OMIM · MGI · Mitocheck · PSORT · PolyMeta · RGD · UniProt · SOURCE · SOSUI · RZPD · Sciencenet · STRING · SMART · TAIR · WikiProfessional · ZFIN Retrieved from http://en..org/wiki/Mendelian_Inheritance_in_Man Categories: Bioinformatics databases | Diagnosis classification Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Català Deutsch Español Français Italiano עברית Magyar Nederlands Polski Português Suomi Svenska УкраїнÑ?ька اردو ä¸æ–‡ This page was last modified on 28 June 2008, at 21:51
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