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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:55:56 - Picrotoxin Picrotoxin Systematic IUPAC name ? Identifiers CAS number 124-87-8 ATC code ? PubChem 5360688 DrugBank APRD00269 Chemical data Formula C30H34O13 Mol. mass 602.583 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? For other uses, see PTX. Picrotoxin, also known as cocculin, is a poisonous crystalline plant alkaloid, first isolated by Boullay in 1812. Found primarily in Cocculus indicus and Anamirta cocculus, it has a strong physiological action. It acts as a non-competitive antagonist of GABA A receptors. As GABA itself is an inhibitory neurotransmitter, infusion of picrotoxin has a stimulative effect. Chemical structure Picrotoxin C30H34O13 consists of two substances, picrotoxinin C15H1606 and picrotin C15H1807. References L. Dupont, O. Dideberg, J. Lamotte-Brasseur et L. Angenot 1976. Structure cristalline et moléculaire de la picrotoxine, C15H16O6.C15H18O7. Acta Cryst. B32: 2987-2993. in French External links Ehrenberger K, Benkoe E, Felix D 1982. Suppressive action of picrotoxin, a GABA antagonist, on labyrinthine spontaneous nystagmus and vertigo in man. Acta Otolaryngol. 93 3-4: 269-73. doi:10.3109/00016488209130882. PMID 7064710. Basic Neurochemistry: GABA Receptor Physiology and Pharmacology This biochemistry article is a stub. Retrieved from http://en..org/wiki/Picrotoxin Categories: GABA antagonists | Biochemistry stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch 日本語 Polski This page was last modified on 22 June 2008, at 15:2
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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