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News About Pneumococcal_polysaccharide_vaccine

20-September-2008 09:55:52 - polysaccharide vaccine Pneumococcal polysaccharide vaccine PPV, also known as Pneumovax, is a vaccine used to prevent Streptococcus pneumoniae pneumococcus infections such as pneumonia and septicaemia. PPV is not the same vaccination as the pneumococcal conjugate vaccine PCV that is routinely administered to infants in the US, Canada, and the UK.1 See further under Children, below. Contents 1 Indications 2 Vaccination schedule 2.1 Adults 2.2 Children 3 Notes and references Indications In the United Kingdom, PPV is recommended as a part of routine vaccination schedules for those over the age of 65, and also for both children and adults in special risk categories: Serious breathing problems Serious heart conditions Severe kidney problems Long term liver disease Diabetes requiring medication Immunosuppression due to disease or treatment e.g. chemotherapy or radio therapy, long-term steroid use, and problems with the spleen asplenia, either because the spleen has been removed splenectomy or does not work properly for example, due to sickle cell disease. Vaccination schedule Adults The 23-valent vaccine e.g., Pneumovax II is only appropriate for adults and usually should only be administered once, as subsequent re-injection risks severe local reactions. The exception is where immunity may be lost at a faster rate than normal e.g. patients with asplenia or nephrotic syndrome when repeated re-vaccination every 5-10 years is recommended. Children Children under the age of two years fail to mount an adequate response to the 23-valent adult vaccine, and instead a 7-valent Pneumococcal Conjugated Vaccine PCV e.g., Prevnar must be used. Whilst this covers only seven strains out of more than ninety strains, these seven strains cause 80% to 90% of cases of severe pneumococcal disease, and it is considered to be nearly 100% effective against these strains.2 Special risk-group Children at special risk e.g. sickle cell disease and asplenia require as full protection as can be achieved using the 7-valent congugated vaccine, with then the more extensive 23-valent vaccine given in the second year of life: Vaccination schedule for children at special risk Age 2-6 months 7-11 months 12-23 months Conjugated vaccine 3 x monthly dose 2 x monthly dose 2 doses, 2 months apart Further dose in second year of life 23-valent vaccine Then after 2nd birthday single dose of 23-valent Routine childhood vaccination programme As of 4 September 2006, PCV is also included in the routine childhood vaccination programme for all children in the UK. In those children not at particular risk, PCV is given at 2, 4 and 13 months of age.3 Notes and references ^ Pneumococcal Conjugate Vaccine: What a Parent Needs to Know - information from the American Academy of Family Physicians website - FamilyDoctor.org. Gives statistics of pneumococcal disease incidence and the occurrence rates of various side effects. ^ Childhood Pneumococcal Disease - information on the disease and the Prevnar vaccine, from the Victoria State Australia government. Includes possible side effects. ^ Full immunisation schedule. NHS September 4, 2006. v d e Vaccines, Vaccination, Immunization, and Inoculation see also artificial induction of immunity Development Adjuvants Cancer vaccines DNA vaccination HIV Live vector vaccine Models Timeline Trial Administration Global: GAVI Policy Schedule Vaccine injury USA: ACIP VAERS VSD Vaccine court Vaccines live Anthrax BCG tuberculosis Flu MMR MMRV PolioOPV Rotavirus Smallpox Varicella Yellow fever Inactivated/toxoid inactivated virus: Flu HAV PolioIPV inactivated bacteria/toxoid: DTwP conjugate: Hib PCV Other subunit: Anthrax DTaP HPV recombinant DNA: HBV other: Anthrax PPV Controversy General A-CHAMP MMR NCVIA Pox party Safe Minds Thiomersal See also List of vaccine topics Epidemiology Eradication of infectious diseases Retrieved from http://en..org/wiki/Pneumococcal_polysaccharide_vaccine Categories: Vaccines Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 14 August 2007, at 08:26

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