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News About Propentofylline

20-September-2008 09:55:58 - Propentofylline Propentofylline Systematic IUPAC name 3-methyl-1-5-oxohexyl-7-propylpurine-2,6-dione Identifiers CAS number 55242-55-2 ATC code N06BC02 PubChem 4938 Chemical data Formula C15H22N4O3 Mol. mass 306.360 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Propentofylline is a xanthine derivative with purported neuroprotective effects. Contents 1 Pharmacology 2 Uses 3 See also 4 References Pharmacology It is a phosphodiesterase inhibitor. It also inhibits adenosine uptake.1 Uses It is being studied as a possible treatment for Alzheimer's disease and multi-infarct dementia.23 Propentofylline has also been studied, to a lesser extent, as a possible adjunct in the treatment of ischemic stroke, due to its vasodilating properties.45 See also Pentoxifylline References ^ Frampton M, Harvey RJ, Kirchner V 2003. Propentofylline for dementia. Cochrane Database Syst Rev 2: CD002853. doi:10.1002/14651858.CD002853. PMID 12804440. ^ Frampton M, Harvey RJ, Kirchner V 2003. Propentofylline for dementia. Cochrane database of systematic reviews Online 2: CD002853. doi:10.1002/14651858.CD002853. PMID 12804440. ^ Kittner B, Rössner M, Rother M 1997. Clinical trials in dementia with propentofylline. Ann. N. Y. Acad. Sci. 826: 307-16. PMID 9329701. ^ Bath PM, Bath-Hextall FJ 2004. Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. Cochrane database of systematic reviews Online 3: CD000162. doi:10.1002/14651858.CD000162.pub2. PMID 15266424. ^ Huber M, Kittner B, Hojer C, Fink GR, Neveling M, Heiss WD 1993. Effect of propentofylline on regional cerebral glucose metabolism in acute ischemic stroke. J. Cereb. Blood Flow Metab. 13 3: 526-30. PMID 8478410. Tablets This pharmacology-related article is a stub. v d e Psychoanaleptics: psychostimulants, agents used for ADHD and nootropics N06B Centrally acting sympathomimetics Amphetamine - Amphetaminil - Atomoxetine - Dextroamphetamine - Dextromethamphetamine - Fencamfamin - Fenozolone - Fenetylline - Methylphenidate - Mesocarb - Pemoline - Pipradrol - Prolintane Xanthine derivatives Caffeine - Propentofylline Glutamate receptor Racetams Aniracetam - Nefiracetam - Oxiracetam - Phenylpiracetam - Piracetam - Pramiracetam Ampakines CX-516 - CX-546 - CX-614 - CX-691 - CX-717 - IDRA-21 - LY-503,430 - PEPA Eugeroics / Benzhydryl compounds Adrafinil - Armodafinil - Modafinil Histamine H3 receptor antagonists ABT-239 - Ciproxifan Other psychostimulants and nootropics Acetylcarnitine - Citicoline - Cyprodenate - Idebenone - Ispronicline - Deanol - Dimebon - Fipexide - Linopirdine - Meclofenoxate - Nizofenone - Pirisudanol - Pyritinol - Sulbutiamine - Taltirelin - Tricyanoaminopropene - Vinpocetine Retrieved from http://en..org/wiki/Propentofylline Categories: Pharmacology stubs | Xanthines Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 2 July 2008, at 03:56

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