Sierra Acai Company
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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:55:50 - Trichlormethiazide Trichlormethiazide Systematic IUPAC name 6-Chloro-3-dichloromethyl-1,1-dioxo- 3,4-dihydro-2H-benzoe1,2,4thiadiazine- 7-sulfonamide Identifiers CAS number 133-67-5 ATC code C03AA03 PubChem 5560 Chemical data Formula C8H8Cl3N3O4S2 Mol. mass 380.6558 g/mol Pharmacokinetic data Bioavailability Variably absorbed from GI tract Metabolism ? Half life ? Excretion Primarily excreted unchanged in urine Therapeutic considerations Pregnancy cat. B D if used to treat pregnancy-induced hypertension Legal status ℞ Prescription only Routes Oral capsules, tablets, oral solution Trichlormethiazide currently being sold under the brand names of Achletin, Diu-Hydrin and Triflumen is a diuretic with properties similar to those of hydrochlorothiazide.1 It is usually administered for the treatment of oedema including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy and hypertension.1 In veterinary medicine, Trichlormethiazide can be combined with Dexamethasone to be used on horses with mild swelling of distal limbs and general bruising.2 Pharmacology As a diuretic in particular a thiazide, trichlormethiazide encourages water loss from the body.1 Trichlormethiazide works by inhibiting Na+/Cl- ion reabsorption from the distal tubules of the kidneys.1 In addition, Trichlormethiazide increases the excretion of potassium.1 Mechanism Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle. This results in excretion of sodium, chloride and water, and thus acts as a diuretic.1 Although Trichlormethiazide is used to treat hypertension, it's hypotensive effects may aren't necessarily due to their role as a diuretic.1 Thiazides in general cause vasodilation by activating calcium-activated potassium channels in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.1 References ^ a b c d e f g h DrugBank: DB01021 Trichlormethiazide. DrugBank. Retrieved on 2008-01-23. ^ Trichlormethiazide and Dexamethasone for veterinary use. Wedgewood Pharmacy. Retrieved on 2008-01-24. v d e Membrane transport modulators Calcium channel blockers Amlodipine Amrinone Anandamide Anipamil Azimilide Bencyclane Benidipine Bepridil Berbamine Bevantolol Canadine Carboxyamido-Triazole Cilnidipine Cinnarizine Clentiazem Conotoxins Darodipine Dauricine Devapamil Diltiazem Dimiapramine Dotarizine Efonidipine Emopamil Enpiperate Eperisone Falipamil Fantofarone Fasudil Felodipine Fenamic acid Fendiline Flunarizine Fosfedil Gabapentin Gallopamil Isradipine Lacidipine Lamotrigine Lercanidipine Lidoflazine Magnesium sulfate Manidipine Manoalide Mepirodipine Mibefradil Monatepil Naftopidil Nicardipine Nifedipine Niguldipine Niludipin Nilvadipine Nimodipine Nisoldipine Nitrendipine Norverapamil Ochratoxin A Octylonium Osthol Oxodipine Perhexiline Pinaverium Piperidine Pranidipine Prenylamine Risedronic acid Ryodipine Sesamodil Stepholidine Terodiline Tetrahydropalmatine Tetrandrine Tolfenamic acid Tranilast Verapamil Potassium channel blockers 3,4-Diaminopyridine 4-Aminopyridine Dofetilide Linopirdine Paxilline Tetraethylammonium Sodium channel blockers Amiloride Encainide Pilsicainide Tetrodotoxin Tocainide Sodium chloride symporter inhibitors Bendroflumethiazide Chlorothiazide Chlorthalidone Cyclopenthiazide Hydrochlorothiazide Hydroflumethiazide Methyclothiazide Polythiazide Trichlormethiazide Sodium potassium chloride symporter inhibitors Bumetanide Furosemide Retrieved from http://en..org/wiki/Trichlormethiazide Categories: Thiazides | Diuretics Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 1 August 2008, at 02:41
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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