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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
10-SEPTEMBER-2008 16:47:15 - Dexketoprofen Dexketoprofen Systematic IUPAC name 2S-2-3-benzoylphenylpropanoic acid Identifiers CAS number ? ATC code M01AE17 PubChem 667550 Chemical data Formula C16H14O3 Mol. mass 254.28056 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status POMUK Routes ? Dexketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug. Contents 1 Indications 2 How does it work 3 Warning 4 Use with caution in 5 Not to be used in 6 Pregnancy and Breastfeeding 7 Label warnings 8 Dose 9 Citations Indications Short-term treatment of mild to moderate pain, including dysmenorrhoea. How does it work Dexketoprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs NSAIDs. It works by blocking the action of a substance in the body called cyclo-oxygenase. Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Warning This medicine may cause dizziness and so may affect your ability to drive or operate machinery safely. Do not drive or operate machinery until you know how this medicine affects you and you are sure it won't affect your performance. For fast relief of pain, take at least 30 minutes before food, as food delays the absorption of this medicine from the gut. This medicine is not for long term use Use with caution in Decreased heart function Disorders involving the formation of blood cells haematopoietic disorders Elderly people Excess retention of water in the body tissues fluid retention History of allergies Long-term inflammation of skin and some internal organs systemic lupus erythematosus Low volume of circulating blood hypovolaemia Mild to moderately decreased liver function Mildly decreased kidney function Syndrome with symptoms of systemic lupus erythematosus, scleroderma, polymyositis, and raynaud's phenomenon mixed connective tissue disease Not to be used in Active bleeding Allergy to aspirin or other medicines in this class Asthma or history of asthma Bleeding disorders Bleeding from the stomach or intestines Breastfeeding Children Crohn's disease History of stomach or duodenal ulcers or indigestion Inflammation of the bowel and back passage Inherited tendency to bleed haemorrhagic diathesis Moderate to severely decreased kidney function Peptic ulcers Pregnancy Severe heart failure Severely decreased liver function This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately. Pregnancy and Breastfeeding Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine. The manufacturer states not to use this medicine during pregnancy and breastfeeding as there is insufficient safety information available. Seek medical advice from your doctor. Label warnings Take this medication half to one hour before food. Dose Adult: 12.5mg every 4-6 hours, or 25mg every 8 hours; max 75mg daily. Elderly: initially max 50mg daily. Child: not recommended. Citations http://www.tiscali.co.uk/lifestyle/healthfitness/health_advice/netdoctor/archive/100003529.html Tablets This pharmacology-related article is a stub. v d e Anti-inflammatory and antirheumatic products M01 Anti-inflammatory and antirheumatic products, non-steroids See also: NSAIDs Pyrazolidine/Butylpyrazolidines: · Ampyrone · Clofezone · Kebuzone · Metamizole · Mofebutazone · Oxyphenbutazone · Phenazone · Phenylbutazone · Sulfinpyrazone · Acetic acid derivatives and related substances: · Aceclofenac · Acemetacin · Alclofenac · Bromfenac · Bumadizone · Bufexamac · Diclofenac · Difenpiramide · Etodolac · Fentiazac · Indometacin · Ketorolac · Lonazolac · Oxametacin · Proglumetacin · Sulindac · Tolmetin · Zomepirac · Oxicams: · Ampiroxicam · Droxicam · Lornoxicam · Meloxicam · Piroxicam · Tenoxicam · Propionic acid derivatives: · Alminoprofen · Benoxaprofen · Dexibuprofen · Dexketoprofen · Fenbufen · Fenoprofen · Flunoxaprofen · Flurbiprofen · Ibuprofen · Ibuproxam · Indoprofen · Ketoprofen · Naproxen · Oxaprozin · Pirprofen · Suprofen · Tiaprofenic acid · Fenamates: · Flufenamic acid · Meclofenamic acid · Mefenamic acid · Tolfenamic acid · Coxibs: · Celecoxib · Etoricoxib · Lumiracoxib · Parecoxib · Rofecoxib · Valdecoxib · other anti-inflammatory and antirheumatic agents, non-steroids: · Nabumetone · Niflumic acid · Azapropazone · Glucosamine · Benzydamine · Glycosaminoglycan · Magnesium salicylate · Proquazone · Superoxide dismutase/Orgotein · Nimesulide · Feprazone · Diacerein · Morniflumate · Tenidap · Oxaceprol · Chondroitin sulfate · Specific antirheumatic agents Quinolines: · Oxycinchophen · Gold preparations: · Sodium aurothiomalate · Sodium aurothiosulfate · Auranofin · Aurothioglucose · Aurotioprol · Penicillamine/Bucillamine v d e Non-steroidal anti-inflammatory drug NSAID products primarily M01A and M02A, also N02BA Salicylates Aspirin acetylsalicylic acid · Aloxiprin · Benorylate · Diflunisal · Ethenzamide · Magnesium salicylate · Methyl salicylate · Salsalate · Salicin · Salicylamide · Sodium salicylate Arylalkanoic acids Diclofenac · Aceclofenac · Acemetacin · Alclofenac · Bromfenac · Etodolac · Indometacin · Indometacin farnesil · Nabumetone · Oxametacin · Proglumetacin · Sulindac · Tolmetin 2-Arylpropionic acids profens Ibuprofen · Alminoprofen · Benoxaprofen · Carprofen · Dexibuprofen · Dexketoprofen · Fenbufen · Fenoprofen · Flunoxaprofen · Flurbiprofen · Ibuproxam · Indoprofen† · Ketoprofen · Ketorolac · Loxoprofen · Miroprofen · Naproxen · Oxaprozin · Pirprofen · Suprofen · Tarenflurbil · Tiaprofenic acid N-Arylanthranilic acids fenamic acids Mefenamic acid · Flufenamic acid · Meclofenamic acid · Tolfenamic acid Pyrazolidine derivatives Phenylbutazone · Ampyrone · Azapropazone · Clofezone · Kebuzone · Metamizole† · Mofebutazone · Oxyphenbutazone · Phenazone · Sulfinpyrazone Oxicams Piroxicam · Droxicam · Lornoxicam · Meloxicam · Tenoxicam · Ampiroxicam COX-2 inhibitors Celecoxib · Deracoxib‡ · Etoricoxib · Firocoxib‡ · Lumiracoxib† · Parecoxib · Rofecoxib† · Valdecoxib† Sulphonanilides Nimesulide Topically used products Bendazac · Diclofenac · Etofenamate · Felbinac · Flurbiprofen · Ibuprofen · Indometacin · Ketoprofen · Naproxen · Piroxicam · Suprofen Others Fluproquazone · COX-inhibiting nitric oxide donator Items listed in bold indicate initially developed compounds of specific groups. †Withdrawn drugs. ‡Veterinary use medications. v d e Analgesic products N02A, N02B Opioids See also: Opioids template Opium Alkaloids Thereof Codeine · Morphine · Opium · Laudanum · Paregoric Semi-Synthetic Opium Derivatives Acetyldihydrocodeine · Benzylmorphine · Desomorphine · Dihydrocodeine · Dihydromorphine · Ethylmorphine · Diamorphine · Hydrocodone · Hydromorphinol · Hydromorphone · Nicocodeine · Nicodicodeine · Nicomorphine · Oxycodone · Oxymorphone · Thebacon Synthetic Opioids Alphaprodine · Anileridine · Buprenorphine · Butorphanol · Dextromoramide · Dextropropoxyphene · Dezocine · Fentanyl · Ketobemidone · Levorphanol · Methadone · Meptazinol · Nalbuphine · Pentazocine · Propoxyphene · Propiram · Pethidine · Phenazocine · Piminodine · Piritramide · Tapentadol · Tilidine · Tramadol Pyrazolones Ampyrone/Aminophenazone · Metamizole · Phenazone Cannabinoids Ajulemic acid · AM404 · Cannabidiol · Cannabis · Nabilone · Tetrahydrocannabinol Anilides Paracetamol acetaminophen · Phenacetin · Propacetamol Non-Steroidal Anti-Inflammatories See also: NSAIDs template Propionic Acid NSAIDs Fenoprofen · Flurbiprofen · Ibuprofen · Ketoprofen · Naproxen · Oxaprozin Oxicam NSAIDs Meloxicam · Piroxicam · Acetic Acid NSAIDs Diclofenac · Indometacin · Ketorolac · Sulindac · Tolmetin COX-2 NSAIDs Celecoxib · Rofecoxib Anthranilic Acid Fenamate NSAIDS Meclofenamate · Mefenamic acid Salicylate NSAIDS Aspirin Acetylsalicylic Acid · Benorylate · Diflunisal · Ethenzamide · Magnesium Salicylate · Salicin · Salicylamide · Salsalate · Trisalate Other NSAIDS Nabumetone Atypical, Adjunct Miscellaneous Bicifadine · Clonidine · Cyclobenzaprine · Duloxetine · Flupirtine · Gabapentin · Glafenine · Nefopam · Orphenadrine · Tebanicline · Trazodone · Ziconotide Retrieved from http://en..org/wiki/Dexketoprofen Categories: Pharmacology stubs | Carboxylic acids Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Türkçe Bosanski Polski Svenska This page was last modified on 2 August 2008, at 18:27
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