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News About Diacerein

10-SEPTEMBER-2008 16:47:15 - Diacerein Diacerein Systematic IUPAC name 4,5-diacetyloxy-9,10-dioxo-anthracene-2- carboxylic acid Identifiers CAS number 13739-02-1 ATC code M01AX21 PubChem 26248 Chemical data Formula C19H12O8 Mol. mass 368.294 g/mol Synonyms Diacetylrhein, diacerhein Pharmacokinetic data Bioavailability ? Protein binding 99% Metabolism Hepatic: deacetylation to rhein, later glucuronidation and sulfate conjugation Half life 4 to 5 hours Excretion Renal 30% Therapeutic considerations Pregnancy cat. Lacking information Legal status Routes Oral Diacerein INN, also known as diacetylrhein, is a drug used in the treatment of osteoarthritis. It works by inhibiting interleukin-1. A 2005 Cochrane review found diacerein to be slightly, but significantly, more effective than placebo in controlling the pain of osteoarthritis.1 Side effects The most common side effects of diacerein treatment are gastrointestinal, such as diarrhea.12 References ^ a b Fidelix TS, Soares BG, Trevisani VF 2006. Diacerein for osteoarthritis. Cochrane database of systematic reviews Online 1: CD005117. doi:10.1002/14651858.CD005117.pub2. PMID 16437519. Free summary ^ French Diacereine. BIAM 1999-03-24. Retrieved on 2007-06-13. v d e Anti-inflammatory and antirheumatic products M01 Anti-inflammatory and antirheumatic products, non-steroids See also: NSAIDs Pyrazolidine/Butylpyrazolidines: · Ampyrone · Clofezone · Kebuzone · Metamizole · Mofebutazone · Oxyphenbutazone · Phenazone · Phenylbutazone · Sulfinpyrazone · Acetic acid derivatives and related substances: · Aceclofenac · Acemetacin · Alclofenac · Bromfenac · Bumadizone · Bufexamac · Diclofenac · Difenpiramide · Etodolac · Fentiazac · Indometacin · Ketorolac · Lonazolac · Oxametacin · Proglumetacin · Sulindac · Tolmetin · Zomepirac · Oxicams: · Ampiroxicam · Droxicam · Lornoxicam · Meloxicam · Piroxicam · Tenoxicam · Propionic acid derivatives: · Alminoprofen · Benoxaprofen · Dexibuprofen · Dexketoprofen · Fenbufen · Fenoprofen · Flunoxaprofen · Flurbiprofen · Ibuprofen · Ibuproxam · Indoprofen · Ketoprofen · Naproxen · Oxaprozin · Pirprofen · Suprofen · Tiaprofenic acid · Fenamates: · Flufenamic acid · Meclofenamic acid · Mefenamic acid · Tolfenamic acid · Coxibs: · Celecoxib · Etoricoxib · Lumiracoxib · Parecoxib · Rofecoxib · Valdecoxib · other anti-inflammatory and antirheumatic agents, non-steroids: · Nabumetone · Niflumic acid · Azapropazone · Glucosamine · Benzydamine · Glycosaminoglycan · Magnesium salicylate · Proquazone · Superoxide dismutase/Orgotein · Nimesulide · Feprazone · Diacerein · Morniflumate · Tenidap · Oxaceprol · Chondroitin sulfate · Specific antirheumatic agents Quinolines: · Oxycinchophen · Gold preparations: · Sodium aurothiomalate · Sodium aurothiosulfate · Auranofin · Aurothioglucose · Aurotioprol · Penicillamine/Bucillamine Tablets This pharmacology-related article is a stub. Retrieved from http://en..org/wiki/Diacerein Categories: Anti-inflammatory agents | Pharmacology stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Türkçe This page was last modified on 23 June 2008, at 22:4

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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.

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