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14-September-2008 10:43:22 - Framingham Heart Study by expanding it. Further information might be found on the talk page or at requests for expansion. July 2008 The Framingham Heart Study is a cardiovascular study based in Framingham, Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of participants. Much of the now-common knowledge concerning heart disease, such as the effects of diet, exercise, and common medications such as aspirin, is based on this longitudinal study. It is a project of the National Heart, Lung, and Blood Institute, in collaboration with since 1971 Boston University. Various health professionals from the hospitals and universities of Greater Boston staff the project. Thomas Royle Dawber was Director of the study from 1949 to 1966. He was appointed as chief epidemiologist shortly after the start of the project, when it was not progressing well.1 The study had been intended to last 20 years, but at that time Dawber moved to Boston and became chairman of preventive medicine, raising funds to continue the project and taking it with him. One of the crucial questions in evidence-based medicine is how closely the people in a study resemble the patient you are dealing with.2 Recently the Framingham studies have become regarded as overestimating risk, particularly in the lower risk groups, for UK populations.3 There has been widespread discussion of the study, and it is generally accepted that the work is outstanding in its scope and duration, and is overall considered very useful. Researchers recently used contact information given by subjects over the last 30 years to map the social network of friends and family in the study.4 The initial population was 5,209 healthy men and women aged 30 to 60, not the whole of the town population, as is sometimes assumed. A similar longitudinal study has been carried out in a high proportion of the residents of Busselton, a town in Western Australia, over a period of many years;5 however, Framingham is more widely cited. Footnotes ^ Richmond 2006. Obituary: Thomas Royle Dawber fee required. BMJ 332: 122. doi:10.1136/bmj.332.7533.122. ^ David Hadden 7 September 2002. Holidays in Framingham?. BMJ 325: 544. doi:10.1136/bmj.325.7363.544. ^ Brindle P, Emberson J, Lampe F, et al 2003. Predictive accuracy of the Framingham coronary risk score in British men: prospective cohort study. BMJ 327 7426: 1267. doi:10.1136/bmj.327.7426.1267. PMID 14644971. ^ Nicholas A. Christakis and James H. Fowler. 2007. The Spread of Obesity in a Large Social Network Over 32 Years, New England Journal of Medicine 357 4: 370-379 ^ A list of publications from the Busselton study References Daniel Levy and Susan Brink. 2005. A Change of Heart: How the People of Framingham, Massachusetts, Helped Unravel the Mysteries of Cardiovascular Disease. Knopf. ISBN 0-375-41275-1. External links Framingham Heart Study - official web site Framingham Heart Study - National Heart, Lung, and Blood Institute Heart Center of MetroWest - Cardiology group including William P. Castelli, MD - Former Director of Framingham Heart Study v d e Framingham, Massachusetts Articles Main · Government · Education · Religion · History Framingham High School · Framingham State College · Marian High School Minuteman statue at the intersection of Main St. and Union Ave. Minuteman statue at the intersection of Main St. and Union Ave. Related Articles Commonwealth of Massachusetts · Middlesex County · MetroWest · Sudbury River Massachusetts State Police · MEMA · Massachusetts Turnpike · The MWRA · Performing Arts Center of Metrowest · Framingham Heart Study · MCI Framingham Businesses Bose · Breyers · CA · IDC · IDG · MetroWest Daily News · Perini · Shoppers World · Staples, Inc. TJX · A.J. Wright · Bob's Stores · HomeGoods · Marshalls · TJ Maxx People Thomas Danforth · Crispus Attucks · Christa McAuliffe · Meta Vaux Warrick Fuller · Solomon Carter Fuller · John Nixon Web sites Main Page · LIFT Public Transit · Fire Department · Parks Recreation Police Department · Public Library · School Department Neighboring Communities Ashland · Dover · Marlborough · Natick · Southborough · Sherborn · Sudbury · Wayland Retrieved from http://en..org/wiki/Framingham_Heart_Study Categories: 1948 establishments | Framingham, Massachusetts | Clinical trialsHidden categories: Articles to be expanded since July 2008 | All articles to be expanded Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Hrvatski This page was last modified on 10 September 2008, at 13:11
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