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09-SEPTEMBER-2008 02:07:44 - disease Autoimmune disease Classification and external resources ICD-9 279.4 OMIM 109100 DiseasesDB 28805 MedlinePlus 000816 MeSH D001327 Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body attacks its own cells. Autoimmune diseases are a major cause of immune-mediated diseases. Contents 1 Gender influence 2 Autoimmune diseases 3 References 4 External links Gender influence Women tend to be affected more often by autoimmune disorders; nearly 79% of autoimmune disease patients in the USA are women. Also they tend to appear during or shortly after puberty. It is not known why this is the case, although hormone levels have been shown to affect the severity of some autoimmune diseases such as multiple sclerosis.1 Other causes may include the presence of fetal cells in the maternal bloodstream. 2 Autoimmune diseases It is possible to classify autoimmune diseases by corresponding type of hypersensitivity: type II, type III, or type IV. No type of autoimmune disease mimics type I hypersensitivity.3 Name Accepted/ suspected Hypersensitivity Autoantibody Acute disseminated encephalomyelitis ADEM Accepted4 Addison's disease Accepted4 Ankylosing spondylitis Accepted4 Antiphospholipid antibody syndrome APS Accepted4 Autoimmune hemolytic anemia Accepted5 II Autoimmune hepatitis Accepted4 Anti-Smooth Muscle Actin Autoimmune inner ear disease Suspected6 Bullous pemphigoid Accepted5 II Anti-Bullous Pemphigoid Antigen 1 and 2 Hemidesmosome antigens Coeliac disease Accepted789 IV Anti-transglutaminase Chagas disease Suspected10 Chronic obstructive pulmonary disease Suspected11 12 Dermatomyositis Accepted13 Diabetes mellitus type 1 Accepted4 IV Endometriosis Suspected14 Goodpasture's syndrome Accepted4 II Anti-Basment Membrane Collagen Type IV Protein Graves' disease Accepted4 II Guillain-Barré syndrome GBS Accepted4 IV Anti-ganglioside Hashimoto's disease Accepted4 IV Hidradenitis suppurativa Suspected15 Idiopathic thrombocytopenic purpura Accepted4 II Interstitial cystitis Suspected16 Lupus erythematosus Accepted4 III Morphea Suspected17 Multiple sclerosis Accepted4 IV Anti-Myelin Basic Protein Myasthenia gravis Accepted4 II Narcolepsy Suspected18 Neuromyotonia Suspected19 Pemphigus Vulgaris Accepted4 II Anti-Desmogein 3 Pernicious anaemia Accepted20 II Polymyositis Accepted13 Primary biliary cirrhosis Accepted21 Anti-p62, Anti-sp100, Anti-MitochondrialM2 Rheumatoid arthritis Accepted4 III Rheumatoid factor Schizophrenia Suspected222324 Scleroderma Suspected17 Anti-topoisomerase Sjögren's syndrome Accepted4 Temporal arteritis also known as giant cell arteritis Accepted4 IV Vasculitis Accepted5 III Vitiligo Suspected2526 Wegener's granulomatosis Accepted27 Anti-neutrophil cytoplasmiccANCA References ^ A Gender Gap in Autoimmunity. Retrieved on 2007-10-19. ^ JAMA -- Abstract: Microchimerism: An Investigative Frontier in Autoimmunity and Transplantation, March 3, 2004, Adams and Nelson 291 9: 1127. Retrieved on 2007-10-19. ^ Parham, Peter 2005. The immune system. New York: Garland Science, 344. ISBN 0-8153-4093-1. ^ a b c d e f g h i j k l m n o p q r MeSH Autoimmune+Diseases ^ a b c Autoimmune Disorders: Immune Disorders: Merck Manual Home ion. ^ Autoimmune Inner Ear Disease, Baylor College of Medicine 1993. ^ Celiac Disease. ^ Meize-Grochowski R 2005. Celiac disease: a multisystem autoimmune disorder. Gastroenterol Nurs 28 5: 394-402; quiz 403-4. PMID 16234635. ^ Sollid LM, Jabri B December 2005. Is celiac disease an autoimmune disorder?. Curr. Opin. Immunol. 17 6: 595-600. doi:10.1016/j.coi.2005.09.015. PMID 16214317. ^ Hyland KV, Engman DM 2006. Further thoughts on where we stand on the autoimmunity hypothesis of Chagas disease. Trends Parasitol. 22 3: 101-2; author reply 103. doi:10.1016/j.pt.2006.01.001. PMID 16446117. ^ Agustà A, MacNee W, Donaldson K, Cosio M. 2003. Hypothesis: does COPD have an autoimmune component?. Thorax 58 10: 832-834. doi:10.1136/thorax.58.10.832. PMID 14514931. ^ Lee SH, Goswami S, Grudo A, et al 2007. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat. Med. 13 5: 567-9. doi:10.1038/nm1583. PMID 17450149. ^ a b Polymyositis and Dermatomyositis: Autoimmune Disorders of Connective Tissue: Merck Manual Home ion. ^ Gleicher N, el-Roeiy A, Confino E, Friberg J 1987. Is endometriosis an autoimmune disease?. Obstetrics and gynecology 70 1: 115-22. PMID 3110710. ^ Clinical Trial: Etanercept in Hidradenitis Suppurativa. Retrieved on 2007-07-08. ^ Kárpáti F, Dénes L, Büttner K 1975. Interstitial cystitis=autoimmune cyatitis? Interstitial as a participating disease in lupus erythematosus in German. Zeitschrift für Urologie und Nephrologie 68 9: 633-9. PMID 1227191. ^ a b Takehara K, Sato S 2005. Localized scleroderma is an autoimmune disorder. Rheumatology Oxford, England 44 3: 274-9. doi:10.1093/rheumatology/keh487. PMID 15561734. ^ Carlander, B., Eliaou J.F., Billiard M. 1993. Autoimmune hypothesis in narcolepsy.. Neurophysiol. Clin. 23: 15. doi:10.1016/S0987-70530580279-5. ^ Maddison P 2006. Neuromyotonia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 117 10: 2118-27. doi:10.1016/j.clinph.2006.03.008. PMID 16843723. ^ MedlinePlus Medical Encyclopedia: Pernicious anemia. Retrieved on 2008-04-05. ^ Primary Biliary Cirrhosis: Fatty Liver, Cirrhosis, and Related Disorders: Merck Manual Home ion. Retrieved on 2008-04-05. ^ Eaton WW, Byrne M, Ewald H, et al 2006. Association of schizophrenia and autoimmune diseases: linkage of Danish national registers. The American journal of psychiatry 163 3: 521-8. doi:10.1176/appi.ajp.163.3.521. PMID 16513876. ^ Jones AL, Mowry BJ, Pender MP, Greer JM 2005. Immune dysregulation and self-reactivity in schizophrenia: do some cases of schizophrenia have an autoimmune basis?. Immunol. Cell Biol. 83 1: 9-17. doi:10.1111/j.1440-1711.2005.01305.x. PMID 15661036. ^ Strous RD, Shoenfeld Y 2006. Schizophrenia, autoimmunity and immune system dysregulation: a comprehensive model updated and revisited. J. Autoimmun. 27 2: 71-80. doi:10.1016/j.jaut.2006.07.006. PMID 16997531. ^ Questions and Answers about Vitiligo. Retrieved on 2007-08-06. ^ A New Gene Linked to Vitiligo and Susceptibility to Autoimmune Disorders - Journal Watch Dermatology. Retrieved on 2007-08-06. ^ Sánchez-Cano D, Callejas-Rubio JL, Ortego-Centeno N April 2008. Effect of rituximab on refractory Wegener granulomatosis with predominant granulomatous disease. J Clin Rheumatol 14 2: 92-3. doi:10.1097/RHU.0b013e31816b4487 inactive 2008-06-25. PMID 18391678. External links Links to pictures of Autoimmune Diseases Hardin MD at University of Iowa v d e Pathology: Immune disorders primarily D80-D89, 273, 279 Immunodeficiency Primary Antibody/humoral B Hypogammaglobulinemia/agammaglobulinemia X-linked, Transient of infancy - Dysgammaglobulinemia IgA, IgG, IgM - Hyper IgM syndrome 1, 2, 5 - Common variable immunodeficiency Cell-mediated T DiGeorge syndrome - Nezelof syndrome - Purine nucleoside phosphorylase deficiency - Ataxia telangiectasia Severe combined B+T x-linked: X-SCID autosomal: Adenosine deaminase deficiency - Omenn syndrome - ZAP70 deficiency - Bare lymphocyte syndrome Complement deficiency Angioedema - Complement 2 deficiency PBD chemotaxis/degranulation Leukocyte adhesion deficiency, Chédiak-Higashi syndrome, Hyper-IgE syndrome respiratory burst Chronic granulomatous disease, Myeloperoxidase deficiency Other ICF syndrome - Wiskott-Aldrich syndrome - WHIM syndrome Acquired AIDS Immunoproliferative Hypergammaglobulinemia Paraproteinemia Cryoglobulinemia, Heavy chain disease, POEMS syndrome, Monoclonal gammopathy of undetermined significance Lymphoproliferative disorders Sarcoidosis Other Hypersensitivity and Autoimmunity/Autoimmune disease See also hematological malignancy and hematology v d e Immune disorders: Hypersensitivity and autoimmune diseases I IgE Allergy Food allergy · Atopy Atopic dermatitis · Anaphylaxis · Urticaria · Hay fever II IgM, IgG ADCC · Pernicious anemia · Hemolytic disease of the newborn · Penicillin allergy autoimmune, cytotoxic: Idiopathic thrombocytopenic purpura · Bullous pemphigoid · Autoimmune hemolytic anemia · Goodpasture's syndrome · Pemphigus vulgaris · Rheumatic fever autoimmune, type 5/receptor: Graves' disease · Myasthenia gravis III Immune complex Serum sickness · Arthus reaction · Hypersensitivity vasculitis · Reactive arthritis · Henoch-Schönlein purpura · Farmer's lung · Post-streptococcal glomerulonephritis autoimmune: Systemic lupus erythematosus · Subacute bacterial endocarditis IV T-cells Contact dermatitis · Cell-mediated immunity · Mantoux test · Graft-versus-host disease autoimmune: Temporal arteritis · Diabetes mellitus type 1 · Hashimoto's thyroiditis · Guillain-Barré syndrome · Multiple sclerosis · Rheumatoid arthritis · Coeliac disease Unknown/ multiple Autoimmune hepatitis · Transplant rejection Retrieved from http://en..org/wiki/Autoimmune_disease Categories: Immune system disorders | Autoimmune diseasesHidden category: Pages with DOIs broken since 2008 Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Español Français Hrvatski עברית Nederlands Polski РуÑ?Ñ?кий SlovenÄ?ina Suomi УкраїнÑ?ька Türkçe This page was last modified on 24 August 2008, at 09:07
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