Sierra Acai Company
Sierra Acai Company
Open 7 Days a Week
MonaVie Independent Distributor
Distributor Training
Shop Online
Enroll Now
Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
Friends
Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
11-SEPTEMBER-2008 13:54:10 - Bile For other uses, see Bile disambiguation. Bile or gall is a bitter yellow or green alkaline fluid secreted by hepatocytes from the liver of most vertebrates. In many species, bile is stored in the gallbladder between meals and upon eating is discharged into the duodenum where the bile aids the process of digestion of lipids. Contents 1 General infomation summary 2 Components- in more detail 3 Production 4 Physiological functions 5 Bile soaps 6 Abnormal conditions associated with bile 7 Four humors 8 See also 9 Footnotes 10 References General infomation summary Bile has various components, some of which are produced by hepatocytes liver cells. Its constituents include: Water Cholesterol Bile pigments Bile salts The bile acids cholate and chenodeoxycholate are typically conjugated with taurine or glycine and are produced by the liver from cholesterol. They are secreted in bile by hepatocytes along the bile canaliculi, which then join the bile duct, and thence into the gall bladder. Ordinarily the concentration of bile salts in bile is 0.8%, however the gall bladder removes water from the bile, concentrating it between meals. It concentrates it up to 5 times increasing concentration to 4%, before contracting the walls and releasing it into the duodenum once chyme has entered the small intestine. Components- in more detail The components of bile: Cholesterol Phospholipids mainly Lecithin Bile pigments bilirubin diglucoronoide Bile salts sodium glycocholate sodium taurocholate Bicarbonate ions Production Digestive system diagram showing the bile duct Digestive system diagram showing the bile duct Bile is produced by hepatocytes in the liver, draining through the many bile ducts that penetrate the liver. During this process, the epithelial cells add a watery solution that is rich in bicarbonates that dilutes and increases alkalinity of the solution. Bile then flows into the common hepatic duct, which joins with the cystic duct from the gallbladder to form the common bile duct. The common bile duct in turn joins with the pancreatic duct to empty into the duodenum. If the sphincter of Oddi is closed, bile is prevented from draining into the intestine and instead flows into the gallbladder, where it is stored and concentrated to up to five times its original potency between meals. This concentration occurs through the absorption of water and small electrolytes, while retaining all the original organic molecules. Cholesterol is also released with the bile, dissolved in the acids and fats found in the concentrated solution. When food is released by the stomach into the duodenum in the form of chyme, the gallbladder releases the concentrated bile to complete digestion. The human liver can produce close to one litre of bile per day depending on body size. 95% of the salts secreted in bile are reabsorbed in the terminal ileum and re-used. Blood from the ileum flows directly to the hepatic portal vein and returns to the liver where the hepatocytes resorb the salts and return them to the bile ducts to be re-used, sometimes two to three times with each meal. Physiological functions Bile salts are composed of a hydrophilic side, and a hydrophobic side. This means that they are more likely to aggregate to form micelles, with the hydrophobic sides towards the centre and hydrophilic towards the outside. In the centre of these micelles are triglycerides, which are separated from a larger globule of lipid, as shown in the diagram. Pancreatic lipase is able to get to the molecules of triglyceride through gaps between the bile salts, providing a largely increased surface area for digestion. Ordinarily, the micelles in the duodenum have a diameter of around 14-33μm. However, it is possible for these to be much smaller, as small as 160nm when using artificial means. Should bile not be present in the duodenum, not all of the lipid is able to be digested during digestion, and a lot of it is passed out in feces. As a result the time taken for the lipid to be broken down would be greatly increased if there was no bile present in the duodenum. This is how the body is able to efficiently digest and absorb lipids for metabolism. Bile acts to some extent as a detergent, helping to emulsify fats increasing surface area to help enzyme action, and thus aids in their absorption in the small intestine. The most important compounds are the salts of taurocholic acid and deoxycholic acid. Bile salts combine with phospholipids to break down fat globules in the process of emulsification by associating its hydrophobic side with lipids and the hydrophilic side with water. Emulsified droplets then are organized into many micelles which increases absorption. Since bile increases the absorption of fats, it is an important part of the absorption of the fat-soluble vitamins D, E, K and A. Besides its digestive function, bile serves as the route of excretion for the hemoglobin breakdown product bilirubin created by breakdown of erythrocytes, which are conjugated by glucuronidation in the liver ; it also neutralises any excess stomach acid before it enters the ileum, the final section of the small intestine. Bile salts are also bacteriocidal to the invading microbes that enter with food. Bile soaps Bile from slaughtered animals can be mixed with soap. This mixture, called bile soap,1 can be applied to textiles a few hours before washing and is a traditional and rather effective method for removing various kinds of tough stains. Abnormal conditions associated with bile The cholesterol contained in bile will occasionally accrete into lumps in the gall bladder, forming gallstones. On an empty stomach, for example, after repeated vomiting caused by excessive consumption of alcohol, Note: The vomiting does not have to be caused by alcohol. If you dry heave long enough, bile will surface a person's vomit may be green or dark yellow, and very bitter. The bitter and greenish component is bile. The color of bile is often likened to fresh-cut grass, but in a vomit it may be mixed with other components in the stomach to look greenish yellow or dark yellow. In the absence of bile, fats become indigestible and are instead excreted in feces, a condition called steatorrhea. Feces lack their characteristic brown colour and instead are white or grey, and greasy.2 Steatorrhea can lead to deficiencies in essential fatty acids and fat-soluble vitamins. In addition, past the small intestine which is normally responsible for absorbing fat from food the gastrointestinal tract and gut flora are not adapted to processing fats, leading to problems in the distal parts of the intestine. Four humors Yellow bile sometimes called ichor and black bile were two of the four vital fluids or humors of ancient and medieval Greco-Roman alternative medicine the other two were phlegm and blood. The Latin names for the terms gave rise to the words choler bile and melancholia black bile. Excessive bile was supposed to produce an aggressive temperament, known as choleric. This is the origin of the word bilious. Depression and other mental illnesses melancholia were ascribed to a bodily surplus of black bile. This is the origin of the word melancholy. See also Bile acid sequestrant Bile bear Intestinal juice Footnotes ^ NEWTON, W. 1837. The invention of certain improvements in the manufacture of soap, which will be particularly applicable to the felting of woollen cloths.. The London Journal Of Arts And Sciences; And Repertory Of Patent Inventions IX: 289. Retrieved on 2007-02-08. ^ Barabote RD, Tamang DG, Abeywardena SN, et al 2006. Extra domains in secondary transport carriers and channel proteins. Biochim. Biophys. Acta 1758 10: 1557-79. doi:10.1016/j.bbamem.2006.06.018. PMID 16905115. References KrejÄ?Ã, Z; HanuÅ¡ L., Podstatová H. Reifová E 1983. A contribution to the problems of the pathogenesis and microbial etiology of cholelithiasis. Acta Universitatis Palackianae Olomucensis Facultatis Medicae 104: 279-286. PMID 6222611. Bowen, R. 2001-11-23. Secretion of Bile and the Role of Bile Acids In Digestion. Retrieved on 2007-07-17. Maton, Anthea; Jean Hopkins, Charles William McLaughlin, Susan Johnson, Maryanna Quon Warner, David LaHart, Jill D. Wright 1993. Human Biology and Health. Englewood Cliffs, New Jersey, USA: Prentice Hall. ISBN 0-13-981176-1. v d e Digestive system, physiology: gastrointestinal physiology Enteric nervous system Meissner's plexus - Auerbach's plexus Exocrine Chief cells Pepsinogen - Parietal cells Gastric acid, Intrinsic factor - Goblet cells Mucus Endocrine/paracrine G cells gastrin, D cells somatostatin - ECL cells Histamine - enterogastrone: I cells CCK, K cells GIP, S cells secretin, Enteroendocrine cells Border Brunner's glands - Paneth cells - Enterocytes Fluids Saliva - Bile - Intestinal juice - Gastric juice - Pancreatic juice Processes Swallowing - Vomiting - Peristalsis Interstitial cell of Cajal - Migrating motor complex - Borborygmus - Gastrocolic reflex - Segmentation contractions - Defecation - Enterohepatic circulation Retrieved from http://en..org/wiki/Bile Categories: Body fluids | Digestive system | Biomolecules | Hepatology Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages العربية Bosanski Català Чăвашла ÄŒesky Dansk Deutsch Ελληνικά Español Esperanto Français עברית Ido Bahasa Indonesia Ã?slenska Italiano Kapampangan Latina Lietuvių Magyar Nederlands 日本語 ‪Norsk bokmÃ¥l‬ ‪Norsk nynorsk‬ Polski Português РуÑ?Ñ?кий Simple English SlovenÄ?ina SlovenÅ¡Ä?ina СрпÑ?ки / Srpski Suomi Svenska తెలà±?à°—à±? ไทย Tiếng Việt Türkçe УкраїнÑ?ька ä¸æ–‡ This page was last modified on 8 September 2008, at 08:2
39 Reasons to Drink Acai Juice Every Day
What is MonaVie - Watch the 8-minute video
Discovering MonaVie Video
The Power of You Video
Effects of MonaVie Active on Antioxidant Capacity in Humans
So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
1. Click on Enroll Now (30 - 55% off retail price)
2. Pay $39 for your Wholesale ID number.
3. NO minimum order required.
4. MonaVie is delivered to your door in 3 to 5 days.