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11-SEPTEMBER-2008 13:54:10 - Globular protein July 2007 3-dimensional structure of haemoglobin, a globular protein. 3-dimensional structure of haemoglobin, a globular protein. Globular proteins, or spheroproteins are one of the two main protein classes, comprising globe-like proteins that are more or less soluble in aqueous solutions where they form colloidal solutions. This main characteristic helps distinguishing them from fibrous proteins the other class, which are practically insoluble. Globular structure and solubility The term globular protein is quite old dating probably from the 19th century and is now somewhat archaic given the hundreds of thousands of proteins and more elegant and descriptive structural motif vocabulary. The globular nature of these proteins can be determined without the means of modern techniques, but only by using ultracentrifuges or dynamic light scattering techniques. The spherical structure is induced by the protein's tertiary structure. The molecule's apolar hydrophobic tails groups are bounded towards the molecule's interior whereas polar hydrophilic heads ones are bound outwards, allowing dipole-dipole interactions with the solvent, which explains the molecule's solubility. A wide range of roles in the organism Unlike fibrous proteins which only play a structural function, globular proteins can act as: Enzymes, by catalyzing organic reactions taking place in the organism in mild conditions and with a great specificity. Different esterases fulfill this role. Messengers, by transmitting messages to regulate biological processes. This function is done by hormones, i.e. insulin etc. Transporters of other molecules through membranes Stocks of amino acids. Regulatory roles are also performed by globular proteins rather than fibrous proteins. Members Among the most known globular proteins is hemoglobin, a member of the globin protein family. Other globular proteins are the immunoglobulins IgA, IgD, IgE, IgG and IgM, and alpha, beta and gamma globulins. See protein electrophoresis for more information on the different globulins. Nearly all enzymes with major metabolic functions are globular in shape, as well as many signal transduction proteins. v d e Proteins Processes Protein biosynthesis - Posttranslational modification - Protein folding - Protein targeting - Proteome - Protein methods Structures Protein structure - Protein structural domains - Proteasome Types List of types of proteins - List of proteins - Membrane protein - Globular protein - Fibrous protein Retrieved from http://en..org/wiki/Globular_protein Categories: Proteins | Protein structure | Molecular biology | ProteomicsHidden category: Articles needing additional references from July 2007 Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages БългарÑ?ки Deutsch Español Français 日本語 SlovenÄ?ina Svenska УкраїнÑ?ька This page was last modified on 13 August 2008, at 21:46
39 Reasons to Drink Acai Juice Every Day
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Effects of MonaVie Active on Antioxidant Capacity in Humans
So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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