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News About AMPA

14-September-2008 18:38:50 - AMPA AMPA IUPAC name alpha-amino-3-hydroxy -5-methyl-4-isoxazole propionic acid Identifiers CAS number 77521-29-0 PubChem 1221 MeSH AMPA ChemSpider ID 1184 Properties Molecular formula C7H10N2O4 Molar mass 186.165 Except where noted otherwise, data are given for materials in their standard state at 25 °C, 100 kPa Infobox references AMPA alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid is a specific agonist for the AMPA receptor. AMPA mimics the effect of glutamate. There are two broad categories of glutamate receptors: ionotropic receptors and metabotropic receptors. Ionotropic receptors are ligand gated channels whose agonists include AMPA, Kainate and NMDA. Metabatropic receptors are G-protein coupled receptors and are separated into individual classes. In the synapse these receptors are believed to serve very different purposes, most of the function is linked to the CNS. AMPA can be used experimentally to distinguish the activity of one receptor from the other in order to understand their differing functions. AMPA generates fast excitatory post synaptic potentials EPSP External links This biochemistry article is a stub. v d e Glutamate receptor ligands Ionotropic NMDA Agonists; NMDA Tetrazolylglycine Antagonists; Competitive antagonists; AP7 APV CGP-37849 Midafotel CPPene PEAQX Perzinfotel PPDA Sdz 220-581 Selfotel; Noncompetitive antagonists; Aptiganel Dizocilpine FPL-12495 FR-115,427 Gacyclidine Hodgkinsine HU-211 Indantadol Psychotridine Remacemide; Uncompetitive channel blockers; 2-MDP 8a-Phenyldecahydroquinoline Amantadine Budipine Delucemine Dexoxadrol Dextromethorphan Dextrorphan Endopsychosin Etoxadrol Eticyclidine Ibogaine Ketamine Memantine NEFA Neramexane Nitrous oxide Phencyclidine Rhynchophylline Riluzole Rolicyclidine Tenocyclidine Tiletamine Xenon; Glycine site antagonists; 1-Aminocyclopropanecarboxylic acid ACEA-1021 7-Chlorokynurenate CGP-39653 DCKA Gavestinel GV-150,526 Kynurenic acid L-689,560 ZD-9379; Polyamine site antagonists; Besonprodil CP-101,606 Eliprodil Ifenprodil Ro25-6981 Traxoprodil; Indirect antagonists; Lubeluzole AMPA Agonists; AMPA Domoic acid 5-Fluorowillardiine; Positive allosteric modulators; Aniracetam Cyclothiazide CX-516 CX-546 CX-614 CX-691 CX-717 IDRA-21 LY-392,098 LY-404,187 LY-451,395 LY-451,646 LY-503,430 Oxiracetam PEPA Piracetam Pramiracetam Antagonists; ATPO CNQX DNQX NBQX Tezampanel LY-293,558; Negative allosteric modulators; GYKI-53,655 Kainate Agonists; 5-Iodowillardiine ATPA Domoic acid Kainic acid LY-339,434 SYM-2081 Antagonists; CNQX DNQX LY-382,884 NBQX NS102 UBP-302; Negative allosteric modulators; NS-3763 Metabotropic Group I Agonists; Unselective; ACPD Dihydroxyphenylglycine; mGlu1 selective; Ro01-6128; mGlu5 selective; CHPG DFB Antagonists; Unselective; MCPG; mGlu1 selective; BAY 36-7620 CPCCOEt LY-367,385; mGlu5 selective; LY-344,545 MPEP MTEP Group II Agonists; Eglumegad LY-354,740 LY-487,379 Antagonists; EGLU LY-341,495 Group III Agonists; Unselective; AP4; mGlu4 selective; PHCCC; mGlu8 selective; DCPG Antagonists; CPPG UBP-1112 Retrieved from http://en..org/wiki/AMPA Categories: AMPA receptor modulators | Biomolecules | Biochemistry stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Français 日本語 ไทย This page was last modified on 9 September 2008, at 04:2

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