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07-SEPTEMBER-2008 03:17:44 - Antipruritic Antipruritics, also known as anti-itch drugs, are medications that inhibit the itching Latin: pruritus that is often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, and mites, and contact dermatitis and urticaria caused by plants such as poison ivy urushiol-induced contact dermatitis or stinging nettle. Contents 1 Common antipruritics 2 Disputed and questionable antipruritics 3 Home remedies 4 References 5 External links Common antipruritics Topical antipruritics in the form of creams and sprays are often available over-the-counter. Oral anti-itch drugs also exist and are usually prescription drugs. The active ingredients usually belong to the following classes: Antihistamines such as diphenhydramine Benadryl Corticosteroids such as hydrocortisone topical cream Local anesthetics such as benzocaine topical cream Lanacaine Counterirritants, such as mint oil, menthol, or camphor1 Calamine lotion, containing zinc oxide and ironIII oxide, is a traditional remedy for mild itching, such as that typically associated with chicken pox - although the USA's Food and Drug Administration has asserted that it has little if any effect.23 Disputed and questionable antipruritics Burow's solution aluminium acetate Olive oil Jewelweed, has been shown to be devoid of any anti-itch activity in several controlled studies 4567 SSRIs selective serotonin reuptake inhibitors comprise a class of medicines commonly used for depression, and are also said to be effective in controlling pruritus in a small number of refractory cases.8 Home remedies Cooling with ice or cold water usually stops the itch for as long as the ice or cold water is appliedcitation needed Heating Slightly painful stimulation like rubbing, slapping or scratching, based on a spinal antagonism between pain- and itch-processing neuronscitation needed References ^ Hercogová J 2005. Topical anti-itch therapy. Dermatologic therapy 18 4: 341-3. doi:10.1111/j.1529-8019.2005.00033.x inactive 2008-06-22. PMID 16297007. ^ American Topics. An Outdated Notion, That Calamine Lotion. Retrieved on 2007-07-19. ^ Appel, L.M. Ohmart and R.F. Sterner, Zinc oxide: A new, pink, refractive microform crystal. AMA Arch Dermatol 73 1956, pp. 316-324. PMID 13301048 ^ D. Long, N. H. Ballentine, J. G. Marks. Treatment of poison ivy/oak allergic contact dermatitis with an extract of jewelweed. Am. J. Contact. Dermat. 83:150-3 1997 PMID 9249283 ^ M. R. Gibson, F. T. Maher. Activity of jewelweed and its enzymes in the treatment of Rhus dermatitis. J. Am. Pharm. Assoc. Am. Pharm. Assoc. 395:294-6 1950 PMID 15421925 ^ J. D. Guin, R. Reynolds. Jewelweed treatment of poison ivy dermatitis. Contact Dermatitis 64:287-8 1980 PMID 6447037 ^ Zink, B. J.; Otten, E.J.; Rosenthal, M.; Singal, B 1991. The Effect Of Jewel Weed In Preventing Poison Ivy Dermatitis. Journal of Wilderness Medicine 2 3: 178-182. Retrieved on 2008-01-16. ^ Lee CS, Koo J 2005. Psychopharmacologic therapies in dermatology: an update. Dermatologic clinics 23 4: 735-44. doi:10.1016/j.det.2005.05.015. PMID 16112451. External links Frontiers in pruritus research: scratching the brain for more effective itch therapy J. Clin. Invest. 116:1174-1185 2006. DOI 10.1172/JCI28553 Tablets This pharmacology-related article is a stub. v d e Major drug groups Gastrointestinal tract/metabolism A stomach acid Antacids, H2 antagonists, Proton pump inhibitors Antiemetics Laxatives Antidiarrhoeals/Antipropulsives Anti-obesity drugs Anti-diabetics Vitamins Dietary minerals Blood and blood forming organs B Antithrombotics Anticoagulants, Antiplatelets, Thrombolytics Antihemorrhagics Cardiovascular system C cardiac therapy/antianginals Cardiac glycosides, Antiarrhythmics, Cardiac stimulant Antihypertensives Diuretics Vasodilators Beta blockers renin-angiotensin system ACE inhibitors, Angiotensin II receptor antagonists, Renin inhibitors Antihyperlipidemics Skin D Emollients Cicatrizant Antipruritics Reproductive system G Hormonal contraception Fertility agents SERMs Sex hormones Endocrine system H Corticosteroids Sex hormones Thyroid hormones Antithyroid agent Infections and infestations J, P Antibiotics Antivirals Vaccines Antifungals Antiparasitic Antiprotozoals, Anthelmintics Malignant and immune disease L Anticancer agents Immunostimulators Immunosuppressants Muscles, bones, and joints M Anabolic steroids Anti-inflammatories NSAID Antirheumatics Corticosteroids Muscle relaxants Brain and nervous system N Anesthetics General, Local Analgesics Anticonvulsants Mood stabilizers Psycholeptic Anxiolytics, Antipsychotics, Hypnotics/Sedatives Psychoanaleptic Antidepressants, Stimulants/Psychostimulants Respiratory system R Bronchodilators Decongestants H1 antagonists Other ATC V Antidotes Contrast media Radiopharmaceuticals Dressing v d e Antipruritics D04 Antihistamines for topical use Thonzylamine - Mepyramine - Thenalidine - Tripelennamine - Chloropyramine - Promethazine - Tolpropamine - Dimetindene - Clemastine - Bamipine - Isothipendyl - Diphenhydramine - Chlorphenoxamine Anesthetics for topical use Lidocaine - Cinchocaine - Oxybuprocaine - Benzocaine - Quinisocaine - Tetracaine - Pramocaine Retrieved from http://en..org/wiki/Antipruritic Categories: Pharmacology stubs | DrugsHidden categories: Pages with DOIs broken since 2008 | All articles with statements | Articles with statements since January 2008 Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Türkçe Català This page was last modified on 1 August 2008, at 23:31
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