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07-SEPTEMBER-2008 03:17:44 - Fifth disease Fifth disease Classification and external resources 16 month old with fifth disease ICD-10 B08.3 ICD-9 057.0 DiseasesDB 4442 eMedicine emerg/378 derm/136 ped/192 Fifth disease is one of several possible manifestations of infection by parvovirus B19.1 The disease is also referred to as erythema infectiosum meaning infectious redness and as slapped cheek syndrome, slapcheek, slap face or slapped face. In Japan the disease is called 'apple sickness or ringo-byou' ã‚Šã‚“ã?”病）in reference to the symptom of facial redness. The name fifth disease derives from its historical classification as the fifth of the classical childhood skin rashes or exanthems. Contents 1 Symptoms 2 Epidemiology 3 References 4 External links Symptoms The bright red cheeks are a defining symptom of the infection in children hence the name slapped cheek disease. Occasionally the rash will extend over the bridge of the nose or around the mouth. In addition to the red cheeks, children often develop a red, lacy rash on the rest of the body, with the upper arms and legs being the most common locations. The rash can last a couple of days some cases lasting for several weeks and may itch. Patients are usually no longer infectious once the rash has appeared. Teenagers and adults may present with a self-limited arthritis. The disease is usually mild,2 but in certain risk groups it can have serious consequences: In pregnant women, infection in the first trimester has been linked to hydrops fetalis, causing spontaneous abortion In people with Sickle-cell disease or other forms of chronic hemolytic anemia, infection can precipitate an aplastic crisis. Epidemiology Any age may be affected although it is most common in children aged five to fifteen years.3 By the time adulthood is reached about half the population will have become immune following infection at some time in their past. Outbreaks can arise especially in nurseries and schools .The Rash is typically described as 'Erythema Infectiosum'. References ^ Weir E March 2005. Parvovirus B19 infection: fifth disease and more. CMAJ 172 6: 743. doi:10.1503/cmaj.045293. PMID 15767606. PMC:552884. ^ Mankuta D, Bar-Oz B, Koren G March 1999. Erythema infectiosum Fifth disease and pregnancy. Can Fam Physician 45: 603-5. PMID 10099795. ^ eMedicine - Pediatrics, Fifth Disease or Erythema Infectiosum : Article by Kenneth T Kwon. External links CDC Parvovirus Information Slapped Cheek Information www.fifthdisease.org NHS Direct health encyclopaedia v d e Infectious diseases - Virus diseases A80-B34, 042-079 CNS Encephalitis/ meningitis DNA virus: Progressive multifocal leukoencephalopathy RNA virus: Subacute sclerosing panencephalitis - Lymphocytic choriomeningitis - Tick-borne meningoencephalitis unknown: Encephalitis lethargica Eye DNA virus: Cytomegalovirus retinitis Other RNA virus: Rabies - Myelitis: Poliomyelitis Post-polio syndrome - Tropical spastic paraparesis Skin and mucous membrane lesions DNA virus, Herpesviridae: Herpes simplex - Chickenpox - Herpes zoster - KSHV DNA virus, other: Poxviridae Smallpox, Monkeypox, Cowpox, Vaccinia, Molluscum contagiosum - exanthem Roseola, Fifth disease - HPV Wart RNA virus: exanthem Measles, Rubella - picornavirus Hand, foot and mouth disease, Foot-and-mouth disease Digestive system Hepatitis DNA virus: B RNA virus: A - D - C - E - G Gastroenteritis DNA virus: Adenovirus RNA virus: Rotavirus - Norovirus - Astrovirus - Coronavirus Respiratory system RNA virus, IV: Acute viral nasopharyngitis - Severe acute respiratory syndrome RNA virus, V: Influenza/Avian influenza - Human parainfluenza viruses - RSV - hMPV Other/varied: Infectious mononucleosis - Viral pneumonia Sexually transmitted DNA virus: HPV Genital warts, Cervical cancer RNA virus, retrovirus: HIV AIDS, AIDS dementia complex - Adult T-cell leukemia Oncovirus DNA virus: Hepatitis B - HPV - Kaposi's sarcoma-associated herpesvirus RNA virus: Hepatitis C - HTLV Systemic DNA virus: Cytomegalovirus RNA virus: Mumps - Bornholm disease - Coxsackie B v d e Exanthema Viral RNA virus: Measles 1st disease - Rubella 3rd disease DNA virus: Slap cheek 5th disease - Roseola 6th disease uncertain: Duke's disease 4th disease Bacterial Scarlet fever 2nd disease v d e Diseases of maternal transmission / perinatal infection / vertical transmission Gestational/ transplacental TORCH infections/TORCH complex Toxoplasmosis, Rubella/Congenital rubella syndrome, Cytomegalovirus, Herpes simplex virus · Hepatitis B virus · Syphilis · Varicella zoster virus · HIV · Fifth disease Transmissible at birth/ transcervical Candidiasis · Gonorrhea · Listeriosis Cell-mediated immunodeficiency of late pregnancy Listeriosis March 2008 Retrieved from http://en..org/wiki/Fifth_disease Categories: Pediatrics | Viral diseasesHidden categories: Articles lacking sources from March 2008 | All articles lacking sources Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Dansk Deutsch Eesti Français Italiano Nederlands 日本語 ‪Norsk bokmÃ¥l‬ Polski Português Suomi Svenska ä¸æ–‡ This page was last modified on 28 August 2008, at 23:12
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