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News About Homovanillic_acid

07-SEPTEMBER-2008 03:17:44 - Homovanillic acid Homovanillic acid IUPAC name 2-4-Hydroxy-3-methoxy-phenylacetic acid Identifiers CAS number 306-08-1 PubChem 1738 MeSH Homovanillic+acid SMILES COC1=CC=CC=C1CC=OOO Properties Molecular formula C9H10O4 Molar mass 182.173 Except where noted otherwise, data are given for materials in their standard state at 25 °C, 100 kPa Infobox references Homovanillic acid HOC6H3OCH3CH2COOH; synonyms: 3-Methoxy-4-hydroxyphenyl acetic acid; HVA; 4-Hydroxy-3-methoxy-benzeneacetic acid; 4-Hydroxy-3-methoxyphenylacetic acid is a major catecholamine metabolite. It is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain. In psychiatry and neuroscience, brain and cerebrospinal fluid levels of HVA are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose.1 HVA presence supports a diagnosis of neuroblastoma and malignant pheochromocytoma. References ^ Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J September 2006. Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia. Schizophr. Res. 86 1-3: 45-53. doi:10.1016/j.schres.2006.05.001. PMID 16806836. This article about an aromatic compound is a stub. v d e Neurotransmitter metabolic intermediates tyrosine→dopamine→epinephrine Dihydroxyphenylalanine - Levodopa - Norepinephrine Catecholamine metabolites epinephrine/norepinephrine: 3,4-Dihydroxymandelic acid - Metanephrine/Normetanephrine - Vanillyl mandelic acid - 3-Methoxy-4-hydroxyphenylglycol dopamine: Dopac - 3-Methoxytyramine - Homovanillic acid tryptophan→serotonin anabolism: 5-Hydroxytryptophan catabolism: 5-Hydroxyindoleacetic acid serotonin→melatonin Normelatonin see also enzymes Retrieved from http://en..org/wiki/Homovanillic_acid Categories: Neurochemistry | Carboxylic acids | Phenols | Ethers | Aromatic compound stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Polski РуÑ?Ñ?кий This page was last modified on 24 July 2008, at 13:51

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