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07-SEPTEMBER-2008 03:17:44 - Lymphadenopathy Symptom/Sign: Lymphadenopathy Classifications and external resources ICD-10 I88., L04., R59.1 ICD-9 289.1-289.3, 683, 785.6 DiseasesDB 22225 eMedicine ped/1333 MeSH D008206 Lymphadenopathy is a term meaning disease of the lymph nodes. It is, however, almost synonymously used with swollen/enlarged lymph nodes. When the infection is of the lymph nodes themselves, it is called lymphadenitis, but when the infection is of the lymph channels, it is called lymphangitis. Contents 1 Associated conditions 2 Patterns of Benign Reactive Lymphadenopathy 3 Bilateral Hilar Lymphadenopathy BHL 3.1 Causes of BHL 4 References Associated conditions Enlarged lymph nodes are a common symptom in a number of infectious and cancerous diseases. It is a recognized symptom of many diseases, which include: reactive: acute infection e.g. bacterial, or viral, or chronic infections tuberculous lymphadenitis, cat-scratch disease. The most distinctive symptom of bubonic plague is extreme swelling of one or more lymph nodes that bulge out of the skin as 'buboes'. The buboes often become necrotic and may even rupture. Infectious mononucleosis is an acute viral infection, the hallmark of which is marked enlargement of the cervical lymph nodes. it is also a symptom of cutaneous anthrax, measles and Human African trypanosomiasis, the latter two giving lymphadenopathy in lymph nodes in the neck toxoplasmosis, a parasitic disease, gives a generalized lymphadenopathy1 tumoral: Primary: Hodgkin lymphoma, non-Hodgkin lymphoma, hairy cell leukemia, give lymphadenopathy in all or a few lymph nodes 1 Secondary: metastasis, Virchow's Node, Neuroblastoma autoimmune etiology: sarcoidosis, systemic lupus erythematosus, rheumatoid arthritis all giving a generalized lymphadenopathy.1 immunocompromised etiology: AIDS. Generalized lymphadenopathy is an early sign of infection with human immunodeficiency virus HIV, the virus that causes acquired immunodeficiency syndrome AIDS. Lymphadenopathy syndrome has been used to describe the first symptomatic stage of HIV progression, preceding AIDS-related complex and full-blown AIDS.2 bites from certain venomous snake species, most notably the black mamba, kraits, Australian brown snakes, coral snakes, tiger snakes, taipans, death adders, and some of the more toxic species of cobra. Patterns of Benign Reactive Lymphadenopathy There are three distinct patterns of benign lymphadenopathy: Follicular hyperplasia. Seen in infections, autoimmune disorders, and nonspecific reactions. Paracortical hyperplasia. Seen in viral infections, skin diseases, and nonspecific reactions. Sinus histiocytosis. Seen in lymph nodes draining limbs, inflammatory lesions, and malignancies. Bilateral Hilar Lymphadenopathy BHL Bilateral hilar lymphadenopathy is a radiographic term that describes the enlargement of mediastinal lymph nodes. It is easily and most commonly identified by a chest x-ray. Causes of BHL The following are causes of BHL:3 Sarcoidosis Infection TB Mycoplasma Malignancy Lymphoma Carcinoma Mediastinal Tumours Organic Dust Disease Silicosis Berylliosis Extrinsic Allergic Alveolitis Such as pigeon fancier's lung Less common causes also exist: needs citation Churg-Strauss syndrome Human Immunodeficiency Virus Extrinsic allergic alveolitis Pneumoconiosis References ^ a b c Status and anamnesis, Anders Albinsson. Page 12 ^ Chris Jennings 1993. Understanding and Preventing AIDS: A Book for Everyone. ^ M. Longmore, I. Wilkinson, T. Turmezei, CK. Cheug 2007. Oxford Handbook of Clinical Medicine 7th ion. United States, New York: Oxford University Press, 179. ISBN 0-19356887-1. v d e Cardiovascular disease: vascular disease - Circulatory system pathology I70-I99, 440-459 Arteries, arterioles and capillaries Arterial occlusive disease/ peripheral vascular disease Arteriosclerosis: Atherosclerosis - Intermittent claudication - Atheroma - Monckeberg's arteriosclerosis Stenosis Renal artery stenosis, Carotid artery stenosis - Fibromuscular dysplasia - Degos disease - Aortoiliac occlusive disease Raynaud's phenomenon/Raynaud's disease - Erythromelalgia Aneurysm Aortic aneurysm/Abdominal aortic aneurysm - Cerebral aneurysm - Coronary artery aneurysm - Intracranial berry aneurysm - Dissection Aortic, Carotid, Vertebral - Pseudoaneurysm Other Arteritis Aortitis - Buerger's disease Arteriovenous fistula - Herary hemorrhagic telangiectasia Nevus Spider angioma, Halo nevus, Cherry angioma Veins Venous thrombosis/ Phlebitis/ Thrombophlebitis primarily lower limb Deep vein thrombosis abdomen May-Thurner syndrome, Portal vein thrombosis, Budd-Chiari syndrome, Renal vein thrombosis upper limb/torso Paget-Schroetter disease, Mondor's disease head Cerebral venous sinus thrombosis Post-thrombotic syndrome Varicose veins Varicocele - Gastric varices - Portacaval anastomosis Hemorrhoid, Esophageal varices, Caput medusae Other Superior vena cava syndrome - Inferior vena cava syndrome - Venous ulcer Arteries or veins Vasculitis - Thrombosis - Embolism Pulmonary embolism, Cholesterol embolism - Angiopathy Macroangiopathy, Microangiopathy Lymphatic disease Lymphadenitis - Lymphedema - Lymphangitis Blood pressure Hypertension Hypertensive heart disease - Hypertensive nephropathy - Secondary hypertension Renovascular hypertension - Pulmonary hypertension Hypotension Orthostatic hypotension See also congenital, neoplasia v d e Diseases of the skin and subcutaneous tissue integumentary system L, 680-709 Infections Staphylococcus Staphylococcal scalded skin syndrome, Impetigo, Boil, Carbuncle - Cellulitis Paronychia - Acute lymphadenitis - Pilonidal cyst - Corynebacterium Erythrasma - Pimple Pustule Bullous disorders acantholysis Pemphigus, Transient acantholytic dermatosis - Pemphigoid Bullous pemphigoid, Mucous membrane pemphigoid - Dermatitis herpetiformis Inflammatory Dermatitis and eczema Atopic dermatitis - Seborrhoeic dermatitis Dandruff, Cradle cap - Contact dermatitis Diaper rash, Urushiol-induced contact dermatitis - Erythroderma - Lichen simplex chronicus/Prurigo nodularis - Itch Pruritus ani - Nummular dermatitis - Dyshidrosis - Pityriasis alba Papulosquamous disorders Psoriasis Psoriatic arthritis - Parapsoriasis Pityriasis lichenoides et varioliformis acuta, Pityriasis lichenoides chronica, Lymphomatoid papulosis - other pityriasis Pityriasis rosea, Pityriasis rubra pilaris - other lichenoid Lichen planus, Lichen nitidus Urticaria and erythema Urticaria: Dermatographic urticaria - Cholinergic urticaria Erythema multiforme/drug eruptions: Stevens-Johnson syndrome - Toxic epidermal necrolysis - Erythema nodosum Other erythema: Erythema annulare centrifugum - Erythema marginatum - Necrolytic migratory erythema - Erythema toxicum Radiation-related disorders Sunburn - Actinic keratosis - Polymorphous light eruption - Radiodermatitis - Erythema ab igne Pigmentation disorder hypopigmentation Albinism, Vitiligo - hyperpigmentation Melasma, Freckle, Café au lait spot, Lentigo/Liver spot, Acanthosis nigricans Other keratosis/hyperkeratosis Seborrheic keratosis, Callus - other epidermal thickening Ichthyosis acquisita, Palmoplantar keratoderma skin ulcer Pyoderma gangrenosum, Bedsore atrophic Lichen sclerosus, Acrodermatitis chronica atrophicans necrobiosis Granuloma annulare, Necrobiosis lipoidica - other granuloma Granuloma faciale, Pyogenic granuloma vasculitis Livedoid vasculitis, Erythema elevatum diutinum Keloid - Systemic lupus erythematosus - Morphea - Calcinosis cutis - Sclerodactyly - Ainhum Disorders of skin appendages Nail Ingrown nail - Onychogryposis - Beau's lines - Yellow nail syndrome - Leukonychia Hair Hair loss Alopecia areata Alopecia totalis, Alopecia universalis, Ophiasis Androgenic alopecia - Hypotrichosis - Telogen effluvium - Traction alopecia - Lichen planopilaris - Trichorrhexis nodosa Other Hypertrichosis Hirsutism Acneiform eruption Acne vulgaris, Chloracne, Blackhead - Rosacea Perioral dermatitis, Rhinophyma follicular cysts Epidermoid cyst, Sebaceous cyst, Steatocystoma multiplex Pseudofolliculitis barbae - Hidradenitis suppurativa - Folliculitis Sweat glands eccrine Miliaria, Anhidrosis - apocrine Body odor, Chromhidrosis, Fox-Fordyce disease see also congenital, neoplasia v d e Symptoms and signs: general R50-R69, 780-789 Fever Hyperpyrexia - Fever of unknown origin Pain Headache - Chronic pain Malaise/Fatigue Asthenia - Debility Fainting/syncope Vasovagal syncope - Carotid sinus syncope - Heat syncope Ingestion food and fluid intake Anorexia, Polydipsia, Polyphagia - Cachexia - Xerostomia Anorexia/Weight loss Hemodynamic Shock: Cardiogenic - Hypovolemic - Distributive Septic, Neurogenic Edema: Peripheral edema - Anasarca Hyperaemia: Functional - Reactive Lymphadenopathy Underdevelopment Delayed milestone - Failure to thrive - Short stature Idiopathic Other Seizure Febrile seizure Hyperhidrosis Sleep hyperhidrosis Clubbing - Tenderness v d e Pathology: lymphatic disease Splenic Asplenia/hyposplenism - Wandering spleen - Polysplenia - Splenomegaly Banti's syndrome Thymus Thymus hyperplasia Lymphocytes -cytosis: Lymphocytosis -penia: Lymphocytopenia Idiopathic CD4+ lymphocytopenia - Lymphoproliferative disorders Lymph nodes Castleman's disease - Lymphangiectasia - Lymphadenopathy|/lymphadenitis Lymph vessels Lymphangitis - Lymphedema Other Tumor lysis syndrome - Pseudolymphoma - Reticuloendotheliosis See also hematological malignancy and immune disorders Retrieved from http://en..org/wiki/Lymphadenopathy Categories: Hematology | Inflammations Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Español Français Bahasa Indonesia עברית Lietuvių Polski Português РуÑ?Ñ?кий This page was last modified on 26 July 2008, at 01:40

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