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07-SEPTEMBER-2008 03:17:44 - Oleamide Oleamide1 IUPAC name Z-Octa-9-decenamide Other names Oleylamide 9-Octadecenamide Z-9-Octadecenamide 9,10-Octadecenoamide Oleic acid amide Identifiers CAS number 301-02-0 PubChem 5283387 EINECS number 206-103-9 SMILES CCCCCCCC\C=C/CCCCCCCC=ON Properties Molecular formula C18H35NO Molar mass 281.48 g mol-1 Appearance Creamy solid Density 2.1 g/cm3 Melting point 102-104 °C Boiling point 200 °C Solubility in water Insoluble Hazards NFPA 704 0 1 0 Flash point 200 °C Except where noted otherwise, data are given for materials in their standard state at 25 °C, 100 kPa Infobox references Oleamide is an endogenous amide of the fatty acid oleic acid. It accumulates in the cerebrospinal fluid during sleep deprivation and induces sleep in animals.2 It is being studied as a potential medical treatment for mood and sleep disorders, and cannabinoid-regulated depression.3 4 The mechanism of action of oleamide's sleep inducing effects is an area of current research. It is likely that oleamide interacts with multiple neurotransmitter systems.5 While structurally related to the endogenous cannabinoid anandamide, the ability of oleamide to bind the cannabinoid receptor CB1 is controversial. Synthetically produced oleamide has a variety of industrial uses including as a slip agent, a lubricant, and a corrosion inhibitor.6 Oleamide was discovered and characterized by Benjamin Cravatt III and Richard Lerner at The Scripps Research Institute in La Jolla, CA. See also Anandamide Fatty acid amide hydrolase References ^ Oleamide at chemicalland21.com ^ Salvador Huitron-Resendiz, Lhys Gombart, Benjamin F. Cravatt, and Steven J. Henriksen 2001. Effect of Oleamide on Sleep and Its Relationship to Blood Pressure, Body Temperature, and Locomotor Activity in Rats. Experimental Neurology 172: 235-243. doi:10.1006/exnr.2001.7792. ^ Methods of treating anxiety and mood disorders with oleamide - US Patent 6359010 ^ Raphael Mechoulam, Ester Fride, Lumir Hanu, Tzviel Sheskin, Tiziana Bisogno, Vincenzo Di Marzo, Michael Bayewitch and Zvi Vogel 1997. Anandamide may mediate sleep induction. Nature 389: 25-26. doi:10.1038/37891. ^ Fedorova I, Hashimoto A, Fecik RA, et al 2001. Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems. J. Pharmacol. Exp. Ther. 299 1: 332-42. PMID 11561096. ^ Surfactants : Westco Oleamide a Slip Agent In Polyethylene Films Retrieved from http://en..org/wiki/Oleamide Categories: Amides | Hypnotics | Lipids Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 13 August 2008, at 00:3
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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