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News About Post_exposure_prophylaxis

07-SEPTEMBER-2008 03:17:44 - exposure prophylaxis This article or section has multiple issues. Please help improve the article or discuss these issues on the talk page. It needs additional references or sources for verification. Tagged since February 2008. It is in need of attention from an expert on the subject. Medicine or the Medicine Portal may be able to help recruit one. Post-exposure prophylaxis PEP is any prophylactic treatment started immediately after exposure to a pathogen such as a disease-causing virus, in order to prevent infection by the pathogen and the development of disease. Contents 1 Rabies 2 HIV 3 See also 4 References Rabies PEP is commonly and very effectively used to prevent the outbreak of rabies after a bite by a rabid animal. The treatment consists of repeated injections of rabies vaccine and immunoglobulin.1 HIV In the case of HIV infection, post-exposure prophylaxis is a course of antiretroviral drugs which is thought to reduce the risk of seroconversion after events with high risk of exposure to HIV e.g., unprotected anal or vaginal sex, needlestick injuries, or sharing needles. To be effective, treatment should begin within an hour2 of possible infection, and no longer than 72 hours post-exposure.citation needed Prophylactic treatment for HIV typically lasts four weeks.3 While there is compelling data to suggest that PEP after HIV exposure is effective, there have been cases where it has failed. Failure has often been attributed to the delay in receiving treatment, the level of exposure i.e., the viral load received, or both. However, for non-occupational exposures, the time and level of exposure are based on patient-supplied information; absolute data is therefore unavailable. PEP can also slow down the development of antibodies, potentially causing false negatives on a later HIV test. Doctors will advise patients who received PEP to get a test at 6 months post-exposude as well as the standard 3 month test. PEP didn't delay seroconversion in any occasion so far. With the evolution in Laboratory Testing a 3 months tests will be sufficient but for legal purposes a final 6 months test will be Conclusive and definitive. The antiretroviral regimen used in PEP see highly active antiretroviral therapy requires close compliance and can have unpleasant side effects including malaise, fatigue, diarrhea, headache, nausea and vomiting.3 Pleasant side effects have been reported within the first 4 days of treatment which mimic anti-depressant properties, however these are rare and none of these effects are known to have been reported past this period.citation needed See also Pre-exposure prophylaxis PrEP References ^ WHO. Retrieved on 2008-03-05. ^ Ignorance of post-exposure prophylaxis guidelines following HIV needlestick injury may increase the risk of seroconversion -- Diprose et al. 84 6: 767 -- British Journal of Anaesthesia. Retrieved on 2008-03-05. ^ a b HIV/AIDS Bureau - HIV Care Pocket Guide 2006 - Occupational HIV Postexposure Prophylaxis PEP. Retrieved on 2008-03-05. Wikiversity At Wikiversity, you can learn about: The allegory of the lookout and post-exposure immunization This medical treatment article is a stub. Retrieved from http://en..org/wiki/Post-exposure_prophylaxis Categories: Medical treatments | HIV/AIDS | Medical treatment stubsHidden categories: Articles lacking reliable references from February 2008 | Medicine articles needing expert attention | All articles with statements | Articles with statements since March 2008 Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Bahasa Indonesia This page was last modified on 5 August 2008, at 16:26

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