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07-SEPTEMBER-2008 03:17:44 - Roseola Roseola Classification and external resources ICD-10 B08.2 ICD-9 057.8 DiseasesDB 5857 MedlinePlus 000968 eMedicine emerg/400 derm/378 ped/998 Roseolovirus Electron micrograph of HHV-6 Electron micrograph of HHV-6 Virus classification Group: Group I dsDNA Family: Herpesviridae Genus: Roseolovirus species Human herpesvirus 6 HHV-6 Human herpesvirus 7 HHV-7 Exanthem subitum meaning sudden rash, also referred to as roseola infantum or rose rash of infants, sixth disease as the sixth rash-causing childhood disease and confusingly baby measles, or three day fever, is a benign disease of children, generally under two years old, whose manifestations are usually limited to a transient rash exanthem that occurs following a fever of about three day's duration. Until recently, its origin was unknown, but it is now known to be caused by two human herpesviruses, HHV-6 Human Herpesvirus Six and HHV-7, also called Roseolovirus. Contents 1 Clinical features 2 Vaccines and treatment 3 Local Terms 4 References 5 External links Clinical features Typically the disease affects a child between six months and three years of age, and begins with a sudden high fever of 102-104 degrees Fahrenheit 39-40 degrees Celsius. This can cause, in rare cases, febrile convulsions also known as febrile seizures or fever fits due to the sudden rise in body temperature, but in many cases the child appears and acts normal. After a few days the fever subsides, and just as the child appears to be recovering, a red rash appears. This usually begins on the trunk, spreading to the legs and neck. The rash is not itchy and may last 1 to 2 days. 1 In contrast, a child suffering from measles would usually appear more infirm, with symptoms of conjunctivitis and a cough, and their rash would affect the face and last for several days. Liver dysfunction can occur in rare cases, and the rare adult who contracts the disease can show signs of mononucleosis. Vaccines and treatment There is no specific vaccine against or treatment for exanthem subitum, and most children with the disease are not seriously ill. A child with fever should be given plenty of fluids to drink. Paracetamol/acetaminophen or ibuprofen could be given to reduce their temperature but never aspirin, due to the risk of Reye's Syndrome2. Fever reduction is usually not needed, because fever is a normal and useful reaction of the body, and if it does not exceed 40 degrees Celsius 104 degrees Fahrenheit, harmless. The rash is not particularly itchy and needs no special lotions or creams. It is likely that many children acquire exanthem subitum subclinically; in other words, they show no outward sign of the disease. Others may be debilitated enough that a doctor's opinion is required to confirm the diagnosis, and particularly to rule out other more serious infections, such as meningitis or measles. In case of febrile seizures, medical advice is essential. Local Terms Philippines: TagalogTigdas Hangin References ^ Roseola - Topic Overview, webmd.com ^ What is the role of aspirin?, reyessyndrome.org A 104 degree temperature can be very dangerous. External links MedlinePlus encyclopedia entry on roseola Links to roseola pictures, Hardin MD/Univ of Iowa Newly Found Herpes Virus Is Called Major Cause of Illness in Young, New York Times HHV-6 Foundation DermNet viral/roseola v d e Infectious diseases - Virus diseases A80-B34, 042-079 CNS Encephalitis/ meningitis DNA virus: Progressive multifocal leukoencephalopathy RNA virus: Subacute sclerosing panencephalitis - Lymphocytic choriomeningitis - Tick-borne meningoencephalitis unknown: Encephalitis lethargica Eye DNA virus: Cytomegalovirus retinitis Other RNA virus: Rabies - Myelitis: Poliomyelitis Post-polio syndrome - Tropical spastic paraparesis Skin and mucous membrane lesions DNA virus, Herpesviridae: Herpes simplex - Chickenpox - Herpes zoster - KSHV DNA virus, other: Poxviridae Smallpox, Monkeypox, Cowpox, Vaccinia, Molluscum contagiosum - exanthem Roseola, Fifth disease - HPV Wart RNA virus: exanthem Measles, Rubella - picornavirus Hand, foot and mouth disease, Foot-and-mouth disease Digestive system Hepatitis DNA virus: B RNA virus: A - D - C - E - G Gastroenteritis DNA virus: Adenovirus RNA virus: Rotavirus - Norovirus - Astrovirus - Coronavirus Respiratory system RNA virus, IV: Acute viral nasopharyngitis - Severe acute respiratory syndrome RNA virus, V: Influenza/Avian influenza - Human parainfluenza viruses - RSV - hMPV Other/varied: Infectious mononucleosis - Viral pneumonia Sexually transmitted DNA virus: HPV Genital warts, Cervical cancer RNA virus, retrovirus: HIV AIDS, AIDS dementia complex - Adult T-cell leukemia Oncovirus DNA virus: Hepatitis B - HPV - Kaposi's sarcoma-associated herpesvirus RNA virus: Hepatitis C - HTLV Systemic DNA virus: Cytomegalovirus RNA virus: Mumps - Bornholm disease - Coxsackie B v d e Exanthema Viral RNA virus: Measles 1st disease - Rubella 3rd disease DNA virus: Slap cheek 5th disease - Roseola 6th disease uncertain: Duke's disease 4th disease Bacterial Scarlet fever 2nd disease Retrieved from http://en..org/wiki/Roseola Categories: Viral diseases | Pediatrics | Herpesviruses Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Français Italiano Nederlands 日本語 Norsk bokmål Polski Português Suomi This page was last modified on 21 August 2008, at 13:19
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