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07-SEPTEMBER-2008 03:17:44 - Zofenopril Zofenopril Systematic IUPAC name 2S,4S-1-2S-3-Benzoylsulfanyl-2-methylpropanoyl-4-phenylsulfanylpyrrolidine-2-carboxylic acid Identifiers CAS number 81872-10-8 ATC code C09AA15 PubChem 92400 Chemical data Formula C22H23NO4S2 Mol. mass 429.552 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes Oral Zofenopril also known as Zofenoprilum Latin is an angiotensin converting enzyme ACE inhibitor with cardioprotective properties indicated for the treatment of hypertension.1 In small studies, zofenopril appeared significantly more effective than the older antihypertensives atenolol and enalapril, and was associated with less adverse effects.23 References ^ Ambrosioni E 2007. Defining the role of zofenopril in the management of hypertension and ischemic heart disorders. Am J Cardiovasc Drugs 7 1: 17-24. PMID 17355163. ^ Nilsson P October 2007. Antihypertensive efficacy of zofenopril compared with atenolol in patients with mild to moderate hypertension. Blood Press Suppl 2: 25-30. PMID 18046976. ^ Mallion JM October 2007. An evaluation of the initial and long-term antihypertensive efficacy of zofenopril compared with enalapril in mild to moderate hypertension. Blood Press Suppl 2: 13-8. PMID 18046974. Structure of captopril, the first clinically successful ACE inhibitor This antihypertensive-related article is a stub. Tablets This pharmacology-related article is a stub. v d e Agents acting on the renin-angiotensin system C09 ACE inhibitors Alacepril Benazepril Captopril Cilazapril Delapril Enalapril Fosinopril Imidapril Lisinopril Moexipril Perindopril Quinapril Ramipril Rentiapril Spirapril Temocapril Trandolapril Zofenopril Angiotensin II receptor antagonists AIIRA Azilsartan Candesartan Eprosartan Irbesartan Losartan Olmesartan Tasosartan Telmisartan Valsartan Renin inhibitors Aliskiren Remikiren Retrieved from http://en..org/wiki/Zofenopril Categories: Antihypertensive agent stubs | Pharmacology stubs | ACE inhibitors Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page This page was last modified on 29 May 2008, at 15:14
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