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14-September-2008 11:27:25 - Brenner tumour Brenner tumour Classification and external resources Brenner tumor of ovary ICD-9 220 ICD-O: 9000 DiseasesDB 33431 MeSH D001948 Brenner tumors are uncommon tumors that are part of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority of these tumors are benign. However, they can be malignant.1 They are most frequently found as incidental findings2 on pelvic examination or at laparotomy. Brenner tumors very rarely can occur in other locations, including testis.3 Contents 1 Presentation 2 Similar conditions 3 Eponym 4 References 5 External links Presentation On gross pathological examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral arising in one ovary, the other is unaffected. The tumors can vary in size from less than 1 cm to 30 cm. Borderline and malignant Brenner tumors are possible but each are rare. Histologically, there are nests of transitional-type epithelial cells with longitudinal nuclear grooves coffee bean nuclei lying in abundant fibrous stroma. Similar conditions Transitional cell carcinoma is an even rarer entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, without the characteristic stromal/epithelial pattern of a Brenner tumor. Eponym It is named for Fritz Brenner, who characterized it in 1907. 4 The term Brenner tumor was first used by Robert Meyer, in 1932.5 References ^ Marwah N, Mathur SK, Marwah S, Singh S, Karwasra RK, Arora B 2005. Malignant Brenner tumour--a case report. Indian J Pathol Microbiol 48 2: 251-2. PMID 16758686. ^ Green GE, Mortele KJ, Glickman JN, Benson CB 2006. Brenner tumors of the ovary: sonographic and computed tomographic imaging features. J Ultrasound Med 25 10: 1245-51; quiz 1252-4. PMID 16998096. ^ Caccamo D, Socias M, Truchet C 1991. Malignant Brenner tumor of the testis and epididymis. Arch. Pathol. Lab. Med. 115 5: 524-7. PMID 2021324. ^ Lamping JD, Blythe JG 1977. Bilateral Brenner tumors: a case report and review of the literature. Hum. Pathol. 8 5: 583-5. doi:10.1016/S0046-81777780117-2. PMID 903146. ^ Philipp, Elliot Elias; O'Dowd, Michael J. 2000. The history of obstetrics and gynaecology. Carnforth, Lancs: Parthenon, 586. ISBN 1-85070-040-0. External links medcyclopaedia Histology at University of Utah v d e Connective/soft tissue tumors and sarcomas ICD-O 8800-9179 C45-C49/D17-D21, 171/214-215 Not otherwise specified 8800-8809 Soft tissue sarcoma - Desmoplastic small round cell tumor Fibromatous 8810-8839 Fibroma/fibrosarcoma - Malignant fibrous histiocytoma - Dermatofibroma/dermatofibrosarcoma - Dermatofibrosarcoma protuberans Myxomatous 8840-8849 Myxoma/myxosarcoma - Angiomyxoma - Ossifying fibromyxoid tumour Lipomatous 8850-8889 Lipoma/liposarcoma Angiomyolipoma Myomatous 8890-8929 Myoma/myosarcoma Leiomyoma/leiomyosarcoma, Rhabdomyoma/rhabdomyosarcoma/Sarcoma botryoides Complex Mixed And Stromal 8930-8999 Adenomyoma - Pleomorphic adenoma - Mixed Müllerian tumor - Mesoblastic nephroma - Wilms' tumor - Rhabdoid tumour - Clear cell sarcoma of the kidney - Hepatoblastoma - Pancreatoblastoma - Carcinosarcoma Fibroepithelial 9000-9039 Brenner tumour - Fibroadenoma - Phyllodes tumor Synovial-like 9040-9049 Synovial sarcoma - Clear cell sarcoma, NOS Mesothelial 9050-9059 Mesothelioma - Adenomatoid tumor Germ cell tumors 9060-9119 Germinomatous Germinoma / Seminoma / Dysgerminoma Nongerminomatous Embryonal carcinoma - Endodermal sinus tumor / Yolk sac tumor - Teratoma / Fetus in fetu / Dermoid cyst / Struma ovarii - Gestational trophoblastic disease Hydatidiform mole - Choriocarcinoma - Polyembryoma - Gonadoblastoma see also disorders v d e Tumors: urogenital neoplasia - genital neoplasia C51-C63/D25-29, 179-187/218-222 Female Ovaries Surface epithelial-stromal tumor, Luteoma, Meigs syndrome, Krukenberg tumor, Teratoma, Clear cell adenocarcinoma, Endometrioid tumor, Fibroma Fallopian tube Primary fallopian tube cancer, Adenomatoid tumor Uterus Uterus Uterine sarcoma, Leiomyosarcoma Endometrium Endometrioid tumor Cervix SCC, Cervical intraepithelial neoplasia Vagina Vagina SCC, Botryoid rhabdomyosarcoma, Adenocarcinoma/Clear cell adenocarcinoma Vulva Vulva Papillary hidradenoma, Extramammary Paget's disease Male Testicles Seminoma - Spermatocytic seminoma - Endodermal sinus tumor yolk sac tumor - Embryonal tumor - Choriocarcinoma - Teratoma - Leydig cell tumor - Sertoli cell tumor Prostate Prostate - Transitional cell carcinoma - Prostatic intraepithelial neoplasia Penis Penis Extramammary Paget's disease Male/female Sex cord-stromal tumour Sertoli-Leydig cell tumour, Thecoma, Granulosa cell tumour - Germ cell tumor - Gonadoblastoma - Brenner tumour - Embryonal carcinoma See also noncongenital, congenital This oncology article is a stub. Retrieved from http://en..org/wiki/Brenner_tumour Categories: Gynecology | Types of cancer | Oncology stubs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Deutsch Polski This page was last modified on 20 July 2008, at 19:47
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