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20-September-2008 10:08:30 - Cyanosis Symptom/Sign: Cyanosis Classifications and external resources ICD-10 R23.0 ICD-9 782.5 Cyanosis is a blue coloration of the skin and mucous membranes due to the presence of deoxygenated hemoglobin in blood vessels near the skin surface. It occurs when the oxygen saturation of arterial blood falls below 85-90% 1.5g/dl deoxyhemoglobin. Although human blood is always a shade of red except in rare cases of hemoglobin-related disease, the optical properties of skin distort the dark red color of deoxygenated blood to make it appear bluish1. The elementary principle behind cyanosis is that deoxygenated hemoglobin is more prone to the optical bluish discoloration, and also produces vasoconstriction that makes it more evident. The scattering of color that produces the blue hue of veins and cyanosis is similar to the process that makes the sky appear blue: some colors are refracted and absorbed more than others. During cyanosis, tissues are uncharacteristically low on oxygen, and therefore tissues that would normally be filled with bright oxygenated blood are instead filled with darker, deoxygenated blood. Darker blood is much more prone to the blue-shifting optical effects2, and thus oxygen deficiency - hypoxia - leads to blue discoloration of the lips and other mucous membranes. The name is derived from the color cyan, the Greek word for blue. Contents 1 Types 1.1 Central cyanosis 1.1.1 Common causes of central cyanosis 1.2 Peripheral cyanosis 1.2.1 Common causes of peripheral cyanosis 2 References 3 See also 4 External links Types Cyanosis can occur in the fingers, including underneath the fingernails, as well as other extremities called peripheral cyanosis, or in the lips and tongue central cyanosis. Central cyanosis Central cyanosis is often due to a circulatory or ventilatory problem that leads to poorer blood oxygenation in the lungs or greater oxygen extraction due to slowing down of blood circulation in the skin's blood vessels. Acute cyanosis can be a result of asphyxiation or choking, and is one of the surest signs that respiration is being blocked. Common causes of central cyanosis Abnormal hemoglobin levels Bronchospasm Congenital heart disease Heart failure Heart valve disease High altitude Hypothermia Hypoventilation Lung disease Myocardial infarction Polycythaemia Pulmonary embolism COPD Emphysema and Chronic Bronchitis Asthma Methemoglobinemia Tetralogy of Fallot Right to left shunts in heart or great vessels Peripheral cyanosis Peripheral cyanosis is the blue tint in fingers or extremities, due to inadequate circulation. The blood reaching the extremities is not oxygen rich and when viewed through the skin a combination of factors can lead to the appearance of a blue color. All factors contributing to central cyanosis can also cause peripheral symptoms to appear, however peripheral cyanosis can be observed without there being heart or lung failures. Small blood vessels may be restricted and can be treated by increasing the normal oxygenation level of the blood. Common causes of peripheral cyanosis All common causes of central cyanosis see above Arterial obstruction Cold exposure due to vasoconstriction Raynaud's phenomenon vasoconstriction Reduced cardiac output e.g. heart failure, hypovolaemia Vasoconstriction Venous obstruction e.g. deep vein thrombosis References ^ Kienle, Alwin; Lothar Lilge, I. Alex Vitkin, Michael S. Patterson, Brian C. Wilson, Raimund Hibst, and Rudolf Steiner March 1, 1996. Why do veins appear blue? A new look at an old question. Applied Optics 35 7: 1151-60. ^ 1 See also Blue baby syndrome Raynaud's phenomenon External links eMedicine Health-cares.net Texas Heart Institute v d e Symptoms and signs: skin and subcutaneous tissue R20-R23, 782 Disturbances of skin sensation Hypoesthesia - Paresthesia - Hyperesthesia Other Rash - Cyanosis - Pallor - Flushing - Petechia - Desquamation - Induration - Diaphoresis Retrieved from http://en..org/wiki/Cyanosis Categories: Medical signs Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages ÄŒesky Deutsch Ù?ارسی Français Italiano Nederlands 日本語 ‪Norsk bokmÃ¥l‬ ‪Norsk nynorsk‬ Polski Português SlovenÄ?ina SlovenÅ¡Ä?ina Svenska УкраїнÑ?ька 䏿–‡ This page was last modified on 16 August 2008, at 12:46
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