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16-September-2008 16:15:17 - Alclometasone Alclometasone Systematic IUPAC name 7-chloro-11-hydroxy- 10,13,16-trimethyl-3-oxo-17- 2-propanoyloxyacetyl- 7,8,9,11,12, 14,15,16- octahydro-6H-cyclopentaaphenanthren-17-yl propanoate Identifiers CAS number 66734-13-2 ATC code D07AB10 S01BA10 PubChem 636374 DrugBank APRD00783 Chemical data Formula C28H37ClO7 Mol. mass 521.042 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes topical Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent. Alclometasone Dipropionate marketed as medication Aclovate by GlaxoSmithKline. Contents 1 Pharmacology 2 Indications 3 Contraindications 4 Side effects 5 How supplied 6 External links Pharmacology Alclometasone inhibits phospholipase A2 by inducing production of lipocortins; inhibits synthesis of arachidonic acid, prostaglandins and leukotrienes acid, reduce release of cytokines from lymphocytes and others mediators of inflammation incl. histamine. Indications Alclometasone cream and onintment are indicated for the relief of corticosteroid-responsive dermatoses, including: atopic dermatitis eczema psoriasis allergic dermatitis contact dermatitis actinic dermatitis kiss-type allergy skin itch Alclometasone may be used on sensetive skin sites face, skinfolds; in pediatric patients 1 year or older and in geriatric patients. Contraindications hypersensitivity to alclometasone or any of ingredients in pharmaceutical forms cutaneous tuberculosis chicken pox perioral dermatitis acne rosacea open wounds trophic ulcers viral infection of skin skin manifestations of syphilis Side effects Alclometasone Adverse reactions/Side effects sometimes, less than 1-2% cases include: burning itching erythema skin reddening xerodermia skin irritation acne hypopigmentation prickly heat folliculitis white atrophy hypertrichosis reinfection of skin How supplied Alclometasone as Aclovate is supplied in: Cream; Topical; 0.05% Ointment; Topical; 0.05% External links v d e Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B Endogenous in CAPS Mineralocorticoids ALDOSTERONE, Deoxycorticosterone, Fludrocortisone Glucocorticoids CORTISONE, HYDROCORTISONE/CORTISOL, DESOXYCORTONE, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Cloprednol, Cortivazol, Deflazacort, Dexamethasone, Fluticasone, Flunisolide, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Meprednisone, Methylprednisolone, Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisolone, Prednisone, Prednylidene, Rimexolone, Triamcinolone Other/ungrouped corticosteroids Alclometasone, Amcinonide, Clobetasol, Clobetasone, Clocortolone, Desonide, Desoximetasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludroxycortide, Flumetasone, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Formocortal, Halcinonide, Halometasone, Loteprednol, Medrysone, Tixocortol, Ulobetasol Aldosterone antagonists Spironolactone, Eplerenone, Potassium canrenoate, Canrenone Retrieved from http://en..org/wiki/Alclometasone Categories: Glucocorticoids Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages This page was last modified on 5 August 2008, at 13:19
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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