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Buy Wholesale and maintain an Active status for 2 months and we will refund your $39 Distributor Fee
20-September-2008 09:29:09 - Nucleoside Redirected from Nucleosides Nitrogenous base Nucleoside Deoxynucleoside Chemical structure of adenine Adenine Chemical structure of adenosine Adenosine A Chemical structure of deoxyadenosine Deoxyadenosine dA Chemical structure of guanine Guanine Chemical structure of guanosine Guanosine G Chemical structure of deoxyguanosine Deoxyguanosine dG Chemical structure of thymine Thymine Chemical structure of 5-methyluridine 5-Methyluridine m5U Chemical structure of thymidine Deoxythymidine dT Chemical structure of uracil Uracil Chemical structure of uridine Uridine U Chemical structure of deoxyuridine Deoxyuridine dU Chemical structure of cytosine Cytosine Chemical structure of cytidine Cytidine C Chemical structure of deoxycytidine Deoxycytidine dC Nucleosides are glycosylamines consisting of a nucleobase often referred to simply base bound to a ribose or deoxyribose sugar. Examples of these include cytidine, uridine, adenosine, guanosine, thymidine and inosine. Nucleosides can be phosphorylated by specific kinases in the cell on the sugar's primary alcohol group -CH2-OH, producing nucleotides, which are the molecular building blocks of DNA and RNA. Nucleosides are produced as the second step in nucleic acid digestion, whereby nucleotidases break down nucleotides such as the thymine nucleotide into nucleosides such as thymidine and phosphate. The nucleosides, in turn, are subsequently broken down: in the lumen of the digestive system by nucleosidases into nucleobases and ribose deoxyribose inside the cell by nucleoside phosphorylases into nitrogenous bases, and ribose-1-phosphate or deoxyribose-1-phosphate. Nucleosides can be produced by combining nucleobases with deoxyribose rings as well. In medicine several nucleoside analogues are used as antiviral or anticancer agents. The viral polymerase incorporates these compounds with non-canon bases. These compounds are activated in the cells by being converted into nucleotides, they are administered as nuclosides since charged nucleotides cannot easily cross cell membranes. In molecular biology several analogues of the sugar back bone exist. Due to the low stability of RNA, which is prone to hydrolysis, several more stable alternative nucleoside/nucleotide analogues are used which correctly bind to RNA. This is achieved by using a different backbone sugar. These analogues include LNA, morpholino, PNA. In sequencing dideoxynucleotides are used. These nucleotides possess a non-canon sugar, dideoxyribose which lacks 3' hydroxyl group which accepts the phosphate and therefore cannot bond with the next base, terminating the chain as DNA polymerases mistake it for a regular deoxyribonucleotide. The structure elements of the nucleosides and the phosphate group bearing nucleotides The structure elements of the nucleosides and the phosphate group bearing nucleotides See also Nucleobase Nucleotide RNA Adenosine triphosphate ATP Nucleic acid analogues v d e Nucleobases, nucleosides, and nucleotides Nucleobases Purine Adenine, Guanine | Pyrimidine Uracil, Thymine, Cytosine Nucleosides/ NB+pentose Ribonucleosides Adenosine | Guanosine | Uridine | Cytidine Deoxyribonucleosides Deoxyadenosine | Deoxyguanosine | Thymidine | Deoxyuridine | Deoxycytidine Nucleotides/ NS+phosphate Ribonucleotide monophosphates AMP, GMP, UMP, CMP | diphosphates ADP, GDP, UDP, CDP | triphosphates ATP, GTP, UTP, CTP Deoxyribonucleotides monophosphates dAMP, dGMP, dUMP, TMP, dCMP | diphosphates dADP, dGDP, TDP, dCDP | triphosphates dATP, dGTP, TTP, dCTP Cyclic cAMP, cGMP, c-di-GMP, cADPR Major families of biochemicals Saccharides | Carbohydrates | Glycosides | | Amino acids | Peptides | Proteins | Glycoproteins | | Lipids | Terpenes | Steroids | Carotenoids Alkaloids | Nucleobases | Nucleic acids | | Enzyme cofactors | Flavonoids | Polyketides | Tetrapyrroles This biochemistry article is a stub. Retrieved from http://en..org/wiki/Nucleoside Categories: Biochemistry stubs | Nucleosides Views Article Discussion this page History Personal tools Log in / create account Navigation Main page Contents Featured content Current events Random article Search Go Search Interaction Community portal Recent changes Contact Donate to Help Toolbox What links here Related changes Upload file Special pages Printable version Permanent link Cite this page Languages Català Česky Dansk Deutsch Ελληνικά Español Français Galego Bahasa Indonesia Italiano ქáƒ?რთული Lietuvių Magyar Nederlands 日本語 Occitan Polski Shqip SlovenÄ?ina Suomi Svenska ä¸æ–‡ This page was last modified on 18 July 2008, at 16:39
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So many of us do not eat a balanced diet, get enough sleep, have too much stress, or are impacted with toxins and pollutants. Drinking 2 ounces of MonaVie twice a day will help your body detoxify as well as build your immune system. Its the smartest thing you can do for yourself, so start today. Buying MonaVie through our company guarantees you support 7 days a week and, if you would like to share MonaVie with your family and friends we will guide you from start to finish.
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